Pharmaceutical Impurity Reference Standards

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Structure Chemical Name CAS MF
N-[1-[(3R)-1-(1-oxo-2-propen-1-yl)-3-piperidinyl]-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl]- 2-Propenamide N-[1-[(3R)-1-(1-oxo-2-propen-1-yl)-3-piperidinyl]-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl]- 2-Propenamide 2031255-27-1 C28H26N6O3
4-amino-5-fluoro-1-((2R,5S)-2-(hydroxymethyl)-3-oxido-1,3-oxathiolan-5-yl)pyrimidin-2(1H)-one 4-amino-5-fluoro-1-((2R,5S)-2-(hydroxymethyl)-3-oxido-1,3-oxathiolan-5-yl)pyrimidin-2(1H)-one C8H11FN3O4S-
Anastrozole Impurity 3 Anastrozole Impurity 3
Cephalexin Impurity 4 Cephalexin Impurity 4 C16H17N3O4S
Rivaroxaban Impurity 42 Rivaroxaban Impurity 42
(R,E)-7-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)-3-hydroxy-5-oxohept-6-enoic acid (R,E)-7-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)-3-hydroxy-5-oxohept-6-enoic acid 1422514-05-3 C22H26FN3O6S
Atorvastatin 2-Fluoro t-Butyl Ester Atorvastatin 2-Fluoro t-Butyl Ester 1099474-28-8 C40H47FN2O5
Cabozantinib Impurity C Cabozantinib Impurity C
(3R,4R)-N,4-dimethyl-piperidin-3-amine (3R,4R)-N,4-dimethyl-piperidin-3-amine 1354469-76-3 C7H16N2
4-(1H-Pyrazol-4-yl)-7H-pyrrolo[2,3-d]pyrimidine 4-(1H-Pyrazol-4-yl)-7H-pyrrolo[2,3-d]pyrimidine 952518-97-7 C9H7N5
5-phenyl-1-(pyridin-3-ylsulfonyl)-1H-pyrrole-3-carbaldehyde 5-phenyl-1-(pyridin-3-ylsulfonyl)-1H-pyrrole-3-carbaldehyde 881676-90-0 C16H12N2O3S
3-Piperidinemethanol, 4-(4-fluorophenyl)-1-methyl-, (3R,4R)- 3-Piperidinemethanol, 4-(4-fluorophenyl)-1-methyl-, (3R,4R)- 100332-12-5 C13H18FNO
r-Cytidine r-Cytidine 13913-16-1 C9H13N3O5
Pyridine, 4-chloro-2-(chloromethyl)-3-methyl- Pyridine, 4-chloro-2-(chloromethyl)-3-methyl- 168167-48-4 C7H7Cl2N
1,2,4-Triazolo(3,4-b)benzothiazole-5-methanol 1,2,4-Triazolo(3,4-b)benzothiazole-5-methanol 69243-49-8 C9H7N3OS
Benzoicacid, 2-sulfino- Benzoicacid, 2-sulfino- 13165-80-5 C7H6O4S
Benzenemethanamine, a-ethyl-N,N-dimethyl- Benzenemethanamine, a-ethyl-N,N-dimethyl- 3330-05-0 C11H17N
CIS-1,2-BIS(AMINOMETHYL)CYCLOBUTANE CIS-1,2-BIS(AMINOMETHYL)CYCLOBUTANE 15286-88-1 C6H14N2
Verapamil Related Compound A (50 mg) (3,4-Dimethoxy-alpha-[3-(methylamino)propyl]-alpha-(1-methylethyl)-benzeneacetonitrile monohydrochloride) Verapamil Related Compound A (50 mg) (3,4-Dimethoxy-alpha-[3-(methylamino)propyl]-alpha-(1-methylethyl)-benzeneacetonitrile monohydrochloride) 67775-97-7 C17H27ClN2O2
Ethanediamide, N1-(5-chloro-2-pyridinyl)-N2-[(1R,2S,4R)-4-[(dimethylamino)carbonyl]-2-[[(4,5,6,7-tetrahydro-5-methylthiazolo[5,4-c]pyridin-2-yl)carbonyl]amino]cyclohexyl]- Ethanediamide, N1-(5-chloro-2-pyridinyl)-N2-[(1R,2S,4R)-4-[(dimethylamino)carbonyl]-2-[[(4,5,6,7-tetrahydro-5-methylthiazolo[5,4-c]pyridin-2-yl)carbonyl]amino]cyclohexyl]- 1255529-23-7 C24H30ClN7O4S
Palonosetron Palonosetron 135729-56-5 C19H22N2O
EthanediaMide, N1-(5-chloro-2-pyridinyl)-N2-[(1R,2S,4S)-4-[(diMethylaMino)carbonyl]-2-[[(4,5,6,7-tetrahydro-5-Methylthiazolo[5,4-c]pyridin-2-yl)carbonyl]aMino]cyclohexyl]- EthanediaMide, N1-(5-chloro-2-pyridinyl)-N2-[(1R,2S,4S)-4-[(diMethylaMino)carbonyl]-2-[[(4,5,6,7-tetrahydro-5-Methylthiazolo[5,4-c]pyridin-2-yl)carbonyl]aMino]cyclohexyl]- 1255529-25-9 C24H30ClN7O4S
N-((3R,4R)-1-benzyl-4-Methylpiperidin-3-yl)-2-chloro-N-Methyl-7H-pyrrolo[2,3-d]pyriMidin-4-aMine N-((3R,4R)-1-benzyl-4-Methylpiperidin-3-yl)-2-chloro-N-Methyl-7H-pyrrolo[2,3-d]pyriMidin-4-aMine 923036-25-3 C20H24ClN5
8-Chloro-11-(piperidin-4-ylidene)-11H-benzo[5,6]cyclohepta[1,2-b]pyridine 8-Chloro-11-(piperidin-4-ylidene)-11H-benzo[5,6]cyclohepta[1,2-b]pyridine 117811-20-8 C19H17ClN2
Fludarabine Phosphate iMpurity B Fludarabine Phosphate iMpurity B 149297-79-0 C5H5N5O
nifedipine iMpurity C nifedipine iMpurity C 111304-31-5 C12H11NO5
RofluMilast related substance RofluMilast related substance 475271-62-6 C16H14Cl2N2O3
Ritonavir EP Impurity I Ritonavir EP Impurity I 165315-26-4 C36H46N6O5S2
(6R-trans)-7-[(2,2-diMethyl-1-oxopropyl)aMino]-3-Methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2- (6R-trans)-7-[(2,2-diMethyl-1-oxopropyl)aMino]-3-Methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2- 146794-70-9 C13H18N2O4S
3-[3-[[[(7S)-3,4-DiMethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]Methyl]MethylaMino]propyl]-1,3-dihydro-7,8-diMethoxy-H-3-benzazepin-2-one 3-[3-[[[(7S)-3,4-DiMethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]Methyl]MethylaMino]propyl]-1,3-dihydro-7,8-diMethoxy-H-3-benzazepin-2-one 1086026-31-4 C27H34N2O5
7-[(3R)-3-[(N-Acetyl)AMino]-1-oxo-4-(2,4,5-trifluorophenyl)butyl]-5,6,7,8-tetrahydro-3-(trifluoroMethyl)-1,2,4-triazolo[4,3-a]pyrazine 7-[(3R)-3-[(N-Acetyl)AMino]-1-oxo-4-(2,4,5-trifluorophenyl)butyl]-5,6,7,8-tetrahydro-3-(trifluoroMethyl)-1,2,4-triazolo[4,3-a]pyrazine 1379666-94-0 C18H17F6N5O2
2-[[Methyl[(3S)-3-(1-naphthalenyloxy)-3-(2-thienyl)propyl]aMino]carbonyl]benzoic Acid 2-[[Methyl[(3S)-3-(1-naphthalenyloxy)-3-(2-thienyl)propyl]aMino]carbonyl]benzoic Acid 199191-67-8 C26H23NO4S
Labetalol IMpurity B Labetalol IMpurity B 802620-01-5 C20H25NO4
Ritonavir EP Impurity C Ritonavir EP Impurity C 1010808-43-1 C25H29N3O4S
AcetaMide, N,N-bis[2-(7-Methoxy-1-naphthalenyl)ethyl]- AcetaMide, N,N-bis[2-(7-Methoxy-1-naphthalenyl)ethyl]- 1385018-58-5 C28H29NO3
(S)-quinuclidin-3-aMine (S)-quinuclidin-3-aMine 120570-05-0 C7H14N2
Benzene, 1-chloro-2-nitroso- Benzene, 1-chloro-2-nitroso- 932-33-2 C6H4ClNO
IMp. A (EP): Ethyl 4-[(11RS)-8-Chloro-11-hydroxy-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl]piperidine-1-carboxylate IMp. A (EP): Ethyl 4-[(11RS)-8-Chloro-11-hydroxy-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl]piperidine-1-carboxylate 38092-95-4 C19H20N2
PeMetrexed EP IMpurity E PeMetrexed EP IMpurity E 182009-04-7 C20H21N5O6
Itraconazole iMpurity A Itraconazole iMpurity A
(S)-BoroLeu-(-)-Pinanediol-CF3COOH (S)-BoroLeu-(-)-Pinanediol-CF3COOH 477254-69-6 C17H29BF3NO4
Butanedioic acid, 2,3-dihydroxy- (2R,3R)-, MonoMethyl ester Butanedioic acid, 2,3-dihydroxy- (2R,3R)-, MonoMethyl ester 3333-46-8 C5H8O6
Valsartan D9 Valsartan D9 1089736-73-1 C24H29N5O3
N-((3S,4S)-1-benzyl-4-Methylpiperidin-3-yl)-N-Methyl-7H-pyrrolo[2,3-d]pyriMidin-4-aMine N-((3S,4S)-1-benzyl-4-Methylpiperidin-3-yl)-N-Methyl-7H-pyrrolo[2,3-d]pyriMidin-4-aMine 1252883-90-1 C20H25N5
P219490 P219490 937370-10-0 C20H21N5Na2O6**
(S)-4-(TERT-BUTOXY)-2-ISOPROPYL-4-OXOBUTANOIC ACID (S)-4-(TERT-BUTOXY)-2-ISOPROPYL-4-OXOBUTANOIC ACID 134807-43-5 C11H20O4
Acarbose D-Fructose IMpurity Acarbose D-Fructose IMpurity 1013621-79-8 C25H43NO18
2,4,6,8-Tetraoxa-5-phosphanonanedioic acid, 5-[[(1R)-2-(6-aMino-9H-purin-9-yl)-1-Methylethoxy]Methyl]-, 1-ethyl 9-(1-Methylethyl) ester, 5-oxide 2,4,6,8-Tetraoxa-5-phosphanonanedioic acid, 5-[[(1R)-2-(6-aMino-9H-purin-9-yl)-1-Methylethoxy]Methyl]-, 1-ethyl 9-(1-Methylethyl) ester, 5-oxide 1422284-16-9 C18H28N5O10P
(R)-α-[2-(1-naphthalenyloxy)ethyl]-benzeneMethanol (R)-α-[2-(1-naphthalenyloxy)ethyl]-benzeneMethanol 156453-53-1 C19H18O2
N-FORMYL-1-(2-AMINO-1-(4-METHOXYPHENYL)ETHYL)CYCLOHEXANOL N-FORMYL-1-(2-AMINO-1-(4-METHOXYPHENYL)ETHYL)CYCLOHEXANOL 272788-07-5 C16H23NO3
Acotiamide  Impurity Acotiamide Impurity 198470-83-6 C20H21N2NaO4S
Terbutaline  Impurity Terbutaline Impurity 52144-90-8 C26H29NO3
methyl (41S,12R,13aR)-13a-ethyl-12-
hydroxy-2,3,41,5,6,12,13,13aoctahydro-
1H-indolo[3,2,1-
de]pyrido[3,2,1-ij][1,5]naphthyridine-
12-carboxylate methyl (41S,12R,13aR)-13a-ethyl-12- hydroxy-2,3,41,5,6,12,13,13aoctahydro- 1H-indolo[3,2,1- de]pyrido[3,2,1-ij][1,5]naphthyridine- 12-carboxylate 83508-83-2 C21H26N2O3
ethyl 4-(5-methyl-3-phenylisoxazol-4-yl)benzenesulfonate ethyl 4-(5-methyl-3-phenylisoxazol-4-yl)benzenesulfonate 473465-11-1 C18H18N2O3S
(1S,2S,3R,5S)-3-(7-((1S,2R)-2-(3,4-difluorophenyl)cyclopropylaMino)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyriMidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol (1S,2S,3R,5S)-3-(7-((1S,2R)-2-(3,4-difluorophenyl)cyclopropylaMino)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyriMidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol 2096989-56-7 C23H28F2N6O4S
Fosaprepitant iMpurity Fosaprepitant iMpurity
Apixaban iMpurity 1 Apixaban iMpurity 1
Azilsartan iMpurity H Azilsartan iMpurity H
Azilsartan iMpurity M Azilsartan iMpurity M
bortezoMib iMpurity F bortezoMib iMpurity F
cefoxitin iMpurity A cefoxitin iMpurity A
3-Morpholinone, 4-(2-aMinophenyl)- 3-Morpholinone, 4-(2-aMinophenyl)- 1082588-73-5 C10H12N2O2
(R)-N-(1-(naphthalen-1-yl)ethyl)-3-(4-(trifluoroMethyl)phenyl)propan-1-aMine (R)-N-(1-(naphthalen-1-yl)ethyl)-3-(4-(trifluoroMethyl)phenyl)propan-1-aMine 1428185-71-0 C22H22F3N
1-Piperidinepropanenitrile, 4-Methyl-3-(Methyl-7H-pyrrolo[2,3-d]pyriMidin-4-ylaMino)-β-oxo- 1-Piperidinepropanenitrile, 4-Methyl-3-(Methyl-7H-pyrrolo[2,3-d]pyriMidin-4-ylaMino)-β-oxo- 344418-92-4 C16H20N6O
Erlotinib impurity A Erlotinib impurity A 183321-85-9 C21H20ClN3O3
1,3-Dioxane-4,6-dione, 5-[[(3,4-diMethoxyphenyl)aMino]Methylene]-2,2-diMethyl- 1,3-Dioxane-4,6-dione, 5-[[(3,4-diMethoxyphenyl)aMino]Methylene]-2,2-diMethyl- 213699-53-7 C15H17NO6
(2R,3R)-2-[(1S)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(4-fluorophenyl)Morpholine hydrochloride (2R,3R)-2-[(1S)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(4-fluorophenyl)Morpholine hydrochloride 1333998-21-2 C20H19ClF7NO2
Budesonide iMpurity Budesonide iMpurity 192057-49-1 C24H32O6
dextroMethorphan iMpurity dextroMethorphan iMpurity
Fluticasone IMpurity Fluticasone IMpurity 397864-58-3 C27H30F2O6S
Valdecoxib iMpurity Valdecoxib iMpurity
Fluconazole IMpurity-H Fluconazole IMpurity-H
Retigabine Dihydrochloride Impurity Retigabine Dihydrochloride Impurity 1432063-93-8 C16H19ClFN3O2
Adrenaline IMpurity F Adrenaline IMpurity F 78995-75-2 C9H13NO5S
Anastrozole IMpurity (alfa1 , alfa1, alfa3, alfa3-TetraMethyl-5-(1H-1,2,4-triazol-1-ylMethyl)-1,3-Benzenediacetic acid) Anastrozole IMpurity (alfa1 , alfa1, alfa3, alfa3-TetraMethyl-5-(1H-1,2,4-triazol-1-ylMethyl)-1,3-Benzenediacetic acid) 1338800-81-9 C17H21N3O4
AtracuriuM IMpurity C1 (trans-Monoacrylate) AtracuriuM IMpurity C1 (trans-Monoacrylate)
AzithroMycin IMpurity C AzithroMycin IMpurity C
AztreonaM IMpurity D AztreonaM IMpurity D
Busulfan IMpurity 1 Busulfan IMpurity 1 1797106-48-9 C6H14O5S2
Deferasirox Ethyl Ester Deferasirox Ethyl Ester 201530-79-2 C23H19N3O4
MetoclopraMide IMpurity F MetoclopraMide IMpurity F 38339-95-6 C13H20ClN3O2
Metronidazole IMpurity E Metronidazole IMpurity E
Propofol IMpurity H Propofol IMpurity H
R-(-)-O-DesMethyl-Venlafaxine-d6 R-(-)-O-DesMethyl-Venlafaxine-d6 1062609-96-4 C16H25NO2
Ribavirin IMp. C (EP) Ribavirin IMp. C (EP)
SalMeterol IMpurity B SalMeterol IMpurity B C25H37NO4
Sitagliptin N-Phoshate IMpurity Sitagliptin N-Phoshate IMpurity 1351498-25-3 C16H16F6N5O4P
SulbactaM IMpurity E SulbactaM IMpurity E
TriMethopriM IMpurity A TriMethopriM IMpurity A 213745-86-9 C15H20N4O3
Varenicline Metadinitro IMpurity Varenicline Metadinitro IMpurity
1-(4-methoxyphenyl)-2-methylpropan-2-amine 1-(4-methoxyphenyl)-2-methylpropan-2-amine 56490-94-9 C11H17NO
product/153101 product/153101
2-Methyl-5,6-dihydro-4H-benzo[b]oxazolo[5,4-d]azepine 2-Methyl-5,6-dihydro-4H-benzo[b]oxazolo[5,4-d]azepine 877858-27-0 C12H12N2O
Apixaban IMpurity(BMS-778960-01) Apixaban IMpurity(BMS-778960-01)
1,3,5-Tri-O-benzoyl-2-deoxy-2-fluoro-α-D-ribofuranose 1,3,5-Tri-O-benzoyl-2-deoxy-2-fluoro-α-D-ribofuranose 704916-12-1 C26H21FO7
Chlorpheniramine Chlorpheniramine 78539-96-5 C16H19ClN2
9-(2,5-d|Dioxo-L-3-aMino-1-pyrrolidineacetic acid)-10-deglycine DaptoMycin 9-(2,5-d|Dioxo-L-3-aMino-1-pyrrolidineacetic acid)-10-deglycine DaptoMycin 121869-35-0 C72H99N17O25
(1S,2S,5S)-4-[2-[2-(6,6-DiMethylbicyclo[3.1.1]hept-2-yl)ethoxy]ethyl]Morpholine (1S,2S,5S)-4-[2-[2-(6,6-DiMethylbicyclo[3.1.1]hept-2-yl)ethoxy]ethyl]Morpholine 38284-47-8 C17H31NO2
[4-(4-AMino-6-hydroxy-7-Methoxy-2-quinazolinyl)-1-piperazinyl](tetrahydro-2-furanyl)Methanone [4-(4-AMino-6-hydroxy-7-Methoxy-2-quinazolinyl)-1-piperazinyl](tetrahydro-2-furanyl)Methanone 105356-89-6 C18H23N5O4
2,2'-[4-(2-Methylpropoxy)-1,3-phenylene]bis[4-Methyl-5-thiazolecarboxylic Acid 5,5'-DiMethyl Ester 2,2'-[4-(2-Methylpropoxy)-1,3-phenylene]bis[4-Methyl-5-thiazolecarboxylic Acid 5,5'-DiMethyl Ester 1330632-47-7 C22H24N2O5S2
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