nifedipine iMpurity C

nifedipine iMpurity C Basic information

Product Name:	nifedipine iMpurity C
Synonyms:	nifedipine iMpurity C;Nifedipine impurity C (EP);APKKCRAKPMSAEI-YFHOEESVSA-N;2'-nitrobenzylideneacetoacetic acid methyl ester;Butanoic acid, 2-[(2-nitrophenyl)methylene]-3-oxo-, methyl ester, (2Z)-;Methyl 2-[(2-Nitrophenyl)methylidene]-3-oxobutanoate;Nifedipine Impurity 56;(Z)-Methyl 2-(2-nitrobenzylidene)-3-oxobutanoate (Nifedipine Impurity)
CAS:	111304-31-5
MF:	C12H11NO5
MW:	249.22
EINECS:
Product Categories:
Mol File:	111304-31-5.mol

nifedipine iMpurity C Chemical Properties

Melting point	90-93 °C(Solv: ethyl acetate (141-78-6); hexane (110-54-3))
Boiling point	395.9±32.0 °C(Predicted)
density	1.296±0.06 g/cm3(Predicted)

Safety Information

MSDS Information

nifedipine iMpurity C Usage And Synthesis

Uses	Methyl 2-[(2-nitrophenyl)methylidene]-3-oxobutanoate is an impurity compound of Nifedipine (N457000). Nifedipine is an antihypertensive and antianginal. A dihydorpyridine calcium channel blocker.

nifedipine iMpurity C Preparation Products And Raw materials

Raw materials	METHYL 2-(O-NITROBENZYLIDENE)-ACETOACETATE-->2-Nitrobenzaldehyde-->Methyl acetoacetate
Preparation Products	Nisoldipine

Nifedipine-d4 (2-nitrophenyl-d4) 6,6-DIBROMOPENICILLANIC ACID Sulbactam sodium (E)-methyl 3-aminobut-2-enoate METHYL 2-(O-NITROBENZYLIDENE)-ACETOACETATE Methyl 3-aminocrotonate Nifedipine Impurity 21 (3S)-6,6-DIBROMO-2,2-DIMETHYLPENAM-3-CARBOXYLIC ACID 1,1-DIOXIDE (S)-(+)-1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic Acid Monomethyl Ester methyl 2,4-bis{2-nitrophenyl}-6-methyl-1,2,3,4-tetrahydro-5-pyrimidinecarboxylate Nifedipine Impurity 9 2,6-Ntp Nifedipine SulbactaM M-1 sodium [2S-(2alpha,5alpha,6beta)]-6-bromo-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate BROMOSULBACTAM NIFEDIPINE-D6 dimethyl 2,6-dimethyl-4-(4-nitrophenyl)-1,4-dihydropyridine-3,5-dicarb oxylate

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