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(S)-quinuclidin-3-aMine

(S)-quinuclidin-3-aMine Basic information
Product Name:(S)-quinuclidin-3-aMine
Synonyms:(S)-quinuclidin-3-aMine;(S)-1-Aza-bicyclo[2.2.2]oct-3-ylamine;(3S)-1-azabicyclo[2.2.2]octan-3-amine;1-Azabicyclo[2.2.2]octan-3-amine, (S)-;(3S)-quinuclidin-3-amine;1-Azabicyclo[2.2.2]octan-3-amine, (3S)-;(3S)-Aminoquinuclidine;Palonosetron Impurity 34
CAS:120570-05-0
MF:C7H14N2
MW:126.2
EINECS:
Product Categories:
Mol File:120570-05-0.mol
(S)-quinuclidin-3-aMine Structure
(S)-quinuclidin-3-aMine Chemical Properties
Boiling point 165.9±8.0 °C(Predicted)
density 1.06±0.1 g/cm3(Predicted)
storage temp. 2-8°C(protect from light)
pka10.58±0.33(Predicted)
Safety Information
MSDS Information
(S)-quinuclidin-3-aMine Usage And Synthesis
Uses(3S)-Aminoquinuclidine is an intermediate used in the synthesis of Palonosetron-3-ene Hydrochloride (P165825), which is an impurity of Palonosetron (P165800), a serotonin 5-HT3 receptor antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). Antiemetic.
(S)-quinuclidin-3-aMine Preparation Products And Raw materials
Preparation ProductsPalonosetron-->(S)-N-(1-Azabicyclo[2.2.2]oct-3-yl)-5,6,7,8-tetrahydro-1-naphthalenecarboxamide
PLSQ-001 TM4-QJ 5,6,7,8-Tetrahydronaphthalene-1-carboxylic acid N,N-Diethyl-5,6,7,8-tetrahydronaphthalene-1-carboxamide (1S)-N-(3S)-1-Azabicyclo[2.2.2]oct-3-yl-1,2,3,4-tetrahydro-1-naphthalenecarboxaMide-d1 (3S)-AMinoquinuclidine-D1 Dihydrochloride 2-((S)-Quinuclidin-3-yl)-2,3,3a,4,5,6-hexahydro-1H-benzo[de]isoquinoline (S)-N-(1-Azabicyclo[2.2.2]oct-3-yl)-5,6,7,8-tetrahydro-1-naphthalenecarboxamide 2H-Naphtho[1,8-bc]furan-2-one, 6,7,8,8a-tetrahydro- (R,S)-Palonosetron Hydrochloride (6R)-Hydroxy (R,S)-Palonosetron (3S)-3-deuterio-N-[dideuterio-[(1S)-1,2,3,4-tetrahydronaphthalen-1-yl]methyl]-1-azabicyclo[2.2.2]octan-3-amine (6S)-Hydroxy (S,S)-Palonosetron 6-Oxo-Palonosetron 1-Naphthalenecarboxylic acid, 5,6,7,8-tetrahydro-8-hydroxy- (6R)-Hydroxy (S,S)-Palonosetron (S)-3-Aminoquinuclidine dihydrochloride N-(3S)-1-Azabicyclo[2.2.2]oct-3-yl-5,6-dihydro-1-Naphthalenecarboxamide (S)-1,2,3,4-Tetrahydro-1-naphthalenemethanol
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