ChemicalBook Product Catalog Analytical Chemistry Standard Pharmaceutical Impurity Reference Standards 2,4,6,8-Tetraoxa-5-phosphanonanedioic acid, 5-[[(1R)-2-(6-aMino-9H-purin-9-yl)-1-Methylethoxy]Methyl]-, 1-ethyl 9-(1-Methylethyl) ester, 5-oxide

2,4,6,8-Tetraoxa-5-phosphanonanedioic acid, 5-[[(1R)-2-(6-aMino-9H-purin-9-yl)-1-Methylethoxy]Methyl]-, 1-ethyl 9-(1-Methylethyl) ester, 5-oxide

2,4,6,8-Tetraoxa-5-phosphanonanedioic acid, 5-[[(1R)-2-(6-aMino-9H-purin-9-yl)-1-Methylethoxy]Methyl]-, 1-ethyl 9-(1-Methylethyl) ester, 5-oxide Basic information
Product Name:2,4,6,8-Tetraoxa-5-phosphanonanedioic acid, 5-[[(1R)-2-(6-aMino-9H-purin-9-yl)-1-Methylethoxy]Methyl]-, 1-ethyl 9-(1-Methylethyl) ester, 5-oxide
Synonyms:2,4,6,8-Tetraoxa-5-phosphanonanedioic acid, 5-[[(1R)-2-(6-aMino-9H-purin-9-yl)-1-Methylethoxy]Methyl]-, 1-ethyl 9-(1-Methylethyl) ester, 5-oxide;((((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)(((ethoxycarbonyl)oxy)methoxy)phosphoryl)oxy)methyl isopropyl carbonate;Tenofovir Disoproxil Fumarate impurity J;1-ethyl 9-(1-Methylethyl) ester;5-oxide;8-Tetraoxa-5-phosphanonanedioic acid;Tenofovir Disoproxil Fumarate IP Impurity M (Base);Tenofovir isoproxil ethyl ester
CAS:1422284-16-9
MF:C18H28N5O10P
MW:505.42
EINECS:
Product Categories:
Mol File:1422284-16-9.mol
2,4,6,8-Tetraoxa-5-phosphanonanedioic acid, 5-[[(1R)-2-(6-aMino-9H-purin-9-yl)-1-Methylethoxy]Methyl]-, 1-ethyl 9-(1-Methylethyl) ester, 5-oxide Structure
2,4,6,8-Tetraoxa-5-phosphanonanedioic acid, 5-[[(1R)-2-(6-aMino-9H-purin-9-yl)-1-Methylethoxy]Methyl]-, 1-ethyl 9-(1-Methylethyl) ester, 5-oxide Chemical Properties
Boiling point 639.5±65.0 °C(Predicted)
density 1.48±0.1 g/cm3(Predicted)
storage temp. Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
form Solid
pka4.20±0.10(Predicted)
color Off-White to Yellow
Stability:Hygroscopic
Safety Information
MSDS Information
2,4,6,8-Tetraoxa-5-phosphanonanedioic acid, 5-[[(1R)-2-(6-aMino-9H-purin-9-yl)-1-Methylethoxy]Methyl]-, 1-ethyl 9-(1-Methylethyl) ester, 5-oxide Usage And Synthesis
UsesTenofovir Disopropyl Ethyl Diester is an impurity of Tenofovir (T018500), an acyclic phosphonate nucleotide analogue and reverse transcriptase inhibitor. Used as an anti-HIV agent. Antiviral.
2,4,6,8-Tetraoxa-5-phosphanonanedioic acid, 5-[[(1R)-2-(6-aMino-9H-purin-9-yl)-1-Methylethoxy]Methyl]-, 1-ethyl 9-(1-Methylethyl) ester, 5-oxide Preparation Products And Raw materials
P-[[(1S)-2-(6-AMino-9H-purin-9-yl)-1-Methylethoxy]Methyl]-phosphonic Acid Monoethyl Ester ((((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)(((isopropoxycarbonyl)oxy)methoxy)phosphoryl)oxy)methyl dimethylcarbamate Tenofovir Disopropyl Ethyl Diester 9H-Purine-9-ethanol, 6-aMino-a-Methyl-, (S)- (((((1-(6-aMino-9H-purin-9-yl)propan-2-yl)oxy)Methyl)phosphoryl)bis(oxy))bis(Methylene) isopropyl Methyl dicarbonate Tenofovir Disoproxil Isopropoxycarbonyl Mono-POC Methyl Tenofovir (Mixture of DiastereoMers) Tenofovir Disoproxil Related Compound B (10 mg) ((E)-9-(Prop-1-enyl)-9H-purin-6-amine) (R)-9-[2-(DIETHYLPHOSPHONOMETHOXY)PROPYL] ADENINE Tenofovir Mono-POC Tenofovir 6-Isopropyl CarbaMate (S)-(((1-(6-aMino-9H-purin-9-yl)propan-2-yloxy)Methyl)phosphoryl)bis(oxy)bis(Methylene) isopropyl dicarbonate Tenofovir Fumarate Mono-POC Tenofovir Tenofovir Disoproxil Dimer nPOC-POC Tenofovir (Mixture of DiastereoMers)
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