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Pharmaceutical Impurity Reference Standards

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Structure Chemical Name CAS MF
Neratinib Impurity 4 Neratinib Impurity 4 1144516-18-6 C31H32ClN6O3+
Avibactam Impurity 3(2R,5S) Avibactam Impurity 3(2R,5S) 1383814-68-3 C7H12N3NaO6S
Linagliptin Impurity C Linagliptin Impurity C 1791405-13-4 C15H20N6O2
1,1-Cyclopropanedicarboxamide,N-[4-[(6,7-dimethoxy-4-quinolinyl)oxy]phenyl]-N'-phenyl- 1,1-Cyclopropanedicarboxamide,N-[4-[(6,7-dimethoxy-4-quinolinyl)oxy]phenyl]-N'-phenyl- 849221-94-9 C28H25N3O5
methyl (41S,12S,13aS)-13a-ethyl-12-hydroxy-8-methoxy-2,3,41,5,6,12,13,13a-octahydro-1H-indolo[3,2,1-de]pyrido[3,2,1-ij][1,5]naphthyridine-12-carboxylate methyl (41S,12S,13aS)-13a-ethyl-12-hydroxy-8-methoxy-2,3,41,5,6,12,13,13a-octahydro-1H-indolo[3,2,1-de]pyrido[3,2,1-ij][1,5]naphthyridine-12-carboxylate 57430-34-9 C22H28N2O4
(R)-1-[3-[4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]ethanone (R)-1-[3-[4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]ethanone 1288338-95-3 C24H24N6O2
Amlodipine Impurity 17 Amlodipine Impurity 17 C26H31ClN2O8S
Edoxaban Impurity 12 (1R,2R,4S) Edoxaban Impurity 12 (1R,2R,4S)
Rivaroxaban Impurity 26 Rivaroxaban Impurity 26 1838133-00-8 C23H21Cl2N3O5S2
Erlotinib Erlotinib 938185-06-9 C16H11N3O2
methyl (41R,12S,13aS)-13a-ethyl-12-hydroxy-2,3,41,5,6,12,13,13a-octahydro-1H-indolo[3,2,1-de]pyrido[3,2,1-ij][1,5]naphthyridine-12-carboxylate methyl (41R,12S,13aS)-13a-ethyl-12-hydroxy-2,3,41,5,6,12,13,13a-octahydro-1H-indolo[3,2,1-de]pyrido[3,2,1-ij][1,5]naphthyridine-12-carboxylate 18374-18-0 C21H26N2O3
Brexpiprazole sulfoxide impurity Brexpiprazole sulfoxide impurity 1191900-51-2 C25H27N3O3S
Cabozantinib Impurity H Cabozantinib Impurity H
Clopidogrel Impurity 11 Clopidogrel Impurity 11 C15H14ClNO2S
Medetomidine Impurity 3 Medetomidine Impurity 3 104245-83-2 C10H13Cl
Tofacitinib Impurity 35 Tofacitinib Impurity 35
ethyl 4-(5-methyl-3-phenylisoxazol-4-yl)benzenesulfonate ethyl 4-(5-methyl-3-phenylisoxazol-4-yl)benzenesulfonate 1884279-18-8 C18H17NO4S
N-methyl-1-(5-phenyl-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl)methanamine fumarate N-methyl-1-(5-phenyl-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl)methanamine fumarate 928325-82-0 C21H21N3O6S
Phenol, 2,4-dibromo-3-methyl- Phenol, 2,4-dibromo-3-methyl- 13321-75-0 C7H6Br2O
N-((4-FLUOROPHENYL)METHYL)ETHANAMIDE N-((4-FLUOROPHENYL)METHYL)ETHANAMIDE 86010-68-6 C9H10FNO
Benzenediazonium, 4-(ethoxycarbonyl)-, chloride Benzenediazonium, 4-(ethoxycarbonyl)-, chloride 2028-79-7 C9H9ClN2O2
2,4-Pteridinediamine,6-(methoxymethyl)- 2,4-Pteridinediamine,6-(methoxymethyl)- 40110-13-2 C8H10N6O
Fingolimod EP Impurity D Fingolimod EP Impurity D 780729-32-0 C21H37NO2
Pentanedioic acid, 2,4-diacetyl-3-(3-nitrophenyl)-, dimethyl ester Pentanedioic acid, 2,4-diacetyl-3-(3-nitrophenyl)-, dimethyl ester 89080-61-5 C17H19NO8
2-Thiazoleacetic acid,4-carboxy-2,5-dihydro-5-(4-hydroxybutylidene)-a-[(1R)-1-hydroxyethyl]-, disodium salt, (aS,2R,5Z)- (9CI) 2-Thiazoleacetic acid,4-carboxy-2,5-dihydro-5-(4-hydroxybutylidene)-a-[(1R)-1-hydroxyethyl]-, disodium salt, (aS,2R,5Z)- (9CI) 130609-10-8 C12H18NNaO6S
4,4'-Iminodiphenol hydrochloride 4,4'-Iminodiphenol hydrochloride 1965310-24-0 C12H12ClNO2
Cefradine Impurity D Cefradine Impurity D
OCTAKIS-6-BROMO-6-DEOXY-GAMMA-CYCLODEXTRIN OCTAKIS-6-BROMO-6-DEOXY-GAMMA-CYCLODEXTRIN 53784-84-2 C48H72Br8O32
2-ETHYNYLANILINE 98 2-ETHYNYLANILINE 98 52670-38-9 C8H7N
Palbociclib Impurity 91 Palbociclib Impurity 91 571191-15-6 C22H27N7O2
Ibrutinib Impurity 28 Ibrutinib Impurity 28 2213398-75-3 C18H15N5O
Clopidogrel Impurity 60 Clopidogrel Impurity 60 1430373-12-8 C25H26ClNO6S
Ozagrel Impurity F Ozagrel Impurity F
Ceftriaxone Sodium impurity 1 Ceftriaxone Sodium impurity 1 1214622-93-1 C10H12N2O5S
Lasoprazole impurity Lasoprazole impurity
677007-73-7 677007-73-7 677007-73-7 C6H4BrClOS
Fluticasone Impurity 14 Fluticasone Impurity 14 C25H31F3O5S
Ritonavir EP Impurity U Ritonavir EP Impurity U
((3R,5S)-7-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenyl carbamoyl)-1H-pyrrol-1-yl)-3,5-dihydroxyheptanoate)calcium(II) ((3R,5S)-7-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenyl carbamoyl)-1H-pyrrol-1-yl)-3,5-dihydroxyheptanoate)calcium(II) C66H68CaF2N4O10
DexMedetoMidine IMpurity O DexMedetoMidine IMpurity O
Rivaroxaban Impurity 48 Rivaroxaban Impurity 48 1414932-72-1 C21H20ClN3O4
Imatinib Impurity A Imatinib Impurity A
Vonoprazan Impurity 19 Vonoprazan Impurity 19
Pregabalin Diacid Pregabalin Diacid 1788341-42-3 C16H26N2O
Dexamethasone Impurity A Dexamethasone Impurity A
Olaparib Impurity 24 Olaparib Impurity 24
Topiroxostat Impurity 6 Topiroxostat Impurity 6
Irinotecan EP Impurity H Irinotecan EP Impurity H
Teneligliptin Impurity 4 Teneligliptin Impurity 4
Erlotinib Hydrochloride iMpurity 53 Erlotinib Hydrochloride iMpurity 53
(3R,4S)-phenyl 3-((benzo[d][1,3]dioxol-5-yloxy)methyl)-4-(4- fluorophenyl)piperidine-1-carboxylate (3R,4S)-phenyl 3-((benzo[d][1,3]dioxol-5-yloxy)methyl)-4-(4- fluorophenyl)piperidine-1-carboxylate 2389152-22-9 C26H24FNO5
Moxifloxacin EP Impurity K Moxifloxacin EP Impurity K
Anestagnate Anestagnate
Trelagliptin IMpurity 33 Trelagliptin IMpurity 33
Estradiol Impurity 1 Estradiol Impurity 1 57780-81-1 C18H24O4
Metoprolol IMpurity L Metoprolol IMpurity L C15H25NO3
Teneligliptin Impurity 14 Teneligliptin Impurity 14
Ampicillin EP Impurity P Ampicillin EP Impurity P
5-Heptenoic acid, 7-[(1R,2R,3R,5S)-2-[(1E)-3,3-difluoro-4-phenoxy-1-buten-1-yl]-3,5-dihydroxycyclopentyl]-, 1-methylethyl ester, (5E)- 5-Heptenoic acid, 7-[(1R,2R,3R,5S)-2-[(1E)-3,3-difluoro-4-phenoxy-1-buten-1-yl]-3,5-dihydroxycyclopentyl]-, 1-methylethyl ester, (5E)- 1563176-58-8 C25H34F2O5
Butanoic acid, 2,2-dimethyl-, (1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-[2-[(2R,4R,5S)-tetrahydro-4-hydroxy-5-methyl-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl ester Butanoic acid, 2,2-dimethyl-, (1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-[2-[(2R,4R,5S)-tetrahydro-4-hydroxy-5-methyl-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl ester 477877-98-8 C26H40O5
1H-1,2,4-Triazole-1-ethanol, α-(2,4-difluorophenyl)-α-(1H-1,2,4-triazol-1-ylmethyl)-, 4-oxide 1H-1,2,4-Triazole-1-ethanol, α-(2,4-difluorophenyl)-α-(1H-1,2,4-triazol-1-ylmethyl)-, 4-oxide 1997296-62-4 C13H12F2N6O2
para-Hydroxy L-Milnacipran para-Hydroxy L-Milnacipran 688738-11-6 C15H22N2O2
Varenicline Impurity 9 Varenicline Impurity 9
Elagolix Sodium impurity3 Elagolix Sodium impurity3
Epinephrine Impurity 4 Epinephrine Impurity 4 94217-53-5 C9H13NO3
(trans)-4-((2-amino-3,6-dibromobenzyl)amino)cyclohexanol (trans)-4-((2-amino-3,6-dibromobenzyl)amino)cyclohexanol C13H18Br2N2O
Recombinant N-Acetyl Alpha-D-Glucosaminidase (NAGLU) Recombinant N-Acetyl Alpha-D-Glucosaminidase (NAGLU)
(2R,3R,4R,5R)-2-(4-amino-2-oxo (2R,3R,4R,5R)-2-(4-amino-2-oxo 1415316-72-1 C12H16N4O7
(R)-2-(3-(diisopropylamino)-1-phenylpropyl)phenol (R)-2-(3-(diisopropylamino)-1-phenylpropyl)phenol C21H29NO
Dexamethasone EP impurities F Dexamethasone EP impurities F
4-amino-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1,3,5-triazin-2(1H)-one compound with (2R,3S,4R,5S)-2-(hydroxymethyl)-5-methyltetrahydrofuran-3,4-diol 4-amino-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1,3,5-triazin-2(1H)-one compound with (2R,3S,4R,5S)-2-(hydroxymethyl)-5-methyltetrahydrofuran-3,4-diol
D-Ribofuranose, 1-C-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-2,3,5-tris-O-(phenylmethyl)- D-Ribofuranose, 1-C-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-2,3,5-tris-O-(phenylmethyl)- 1355049-94-3 C32H32N4O5
Delamanid Impurity 1 Delamanid Impurity 1
N-[4-[(6,7-Dimethoxy-4-quinolinyl)oxy]phenyl]-N'-(4-fluoro-3-hydroxyphenyl)-1,1-cyclopropanedicarboxamide N-[4-[(6,7-Dimethoxy-4-quinolinyl)oxy]phenyl]-N'-(4-fluoro-3-hydroxyphenyl)-1,1-cyclopropanedicarboxamide 1628530-41-5 C28H24FN3O6
Oseltamivir Impurity Mixture (MW:486 Da) Oseltamivir Impurity Mixture (MW:486 Da)
2,2'-(7-((2R,3S)-1,3,4-trihydroxybutan-2-yl)-10-((2S,3R)-1,3,4-trihydroxybutan-2-yl)-1,4,7,10-tetraazacyclododecane-1,4-diyl)diacetic acid Gd3+ 2,2'-(7-((2R,3S)-1,3,4-trihydroxybutan-2-yl)-10-((2S,3R)-1,3,4-trihydroxybutan-2-yl)-1,4,7,10-tetraazacyclododecane-1,4-diyl)diacetic acid Gd3+
(R)-Ethyl 3-(bromomethyl)hexanoate (R)-Ethyl 3-(bromomethyl)hexanoate 1956435-91-8 C9H17BrO2
Flucloxacillin Sodium EP Impurity B Flucloxacillin Sodium EP Impurity B
Acyclovir Impurity 15 Acyclovir Impurity 15
Brivaracetam Impurity 5 Brivaracetam Impurity 5 1942054-60-5 C7H13BrO2
(S,E)-7-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)-5-hydroxyhept-2-enoic acid calcium(II) (S,E)-7-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)-5-hydroxyhept-2-enoic acid calcium(II) 1659317-57-3 C33H35CaFN2O4
Epalrestat Impurity 4 Epalrestat Impurity 4 130786-32-2 C8H9NO3S2
Apixaban Impurity 73 Apixaban Impurity 73 1998079-13-2 C44H40N8O8
Alectinib Impurity 10 Alectinib Impurity 10 1256584-81-2 C28H29N3O3
Acemetacin Impurity C Acemetacin Impurity C
NA NA
Vonoprazan Impurity 58 Vonoprazan Impurity 58
Tafluprost Impurity 12 Tafluprost Impurity 12
IOHEXOL RELATED COMPOUND C (100 MG) (N,N'- BIS(2,3-DIHYDROXYPROPYL)-5-NITRO-1,3-BENZENEDI- CARBOXAMIDE) IOHEXOL RELATED COMPOUND C (100 MG) (N,N'- BIS(2,3-DIHYDROXYPROPYL)-5-NITRO-1,3-BENZENEDI- CARBOXAMIDE)
N-(4-AMINO-6,7-DIMETHOXYQUINAZOL-2-YL)-N-METHYL-PROPYLENEDIAMINE, HYDROCHLORIDE N-(4-AMINO-6,7-DIMETHOXYQUINAZOL-2-YL)-N-METHYL-PROPYLENEDIAMINE, HYDROCHLORIDE 81403-69-2 C14H22ClN5O2
FAMOTIDINE RELATED COMPOUND B FAMOTIDINE RELATED COMPOUND B 89268-62-2 C16H23N11O2S5
TIZOXANIDE GLUCURONIDE, SODIUM SALT TIZOXANIDE GLUCURONIDE, SODIUM SALT 221287-83-8 C16H14N3NaO10S
ETHYL (2E)-CHLORO(PHENYLHYDRAZONO)ACETATE ETHYL (2E)-CHLORO(PHENYLHYDRAZONO)ACETATE 28663-68-5 C10H11ClN2O2
Sugammadex sodium Impurity 50 Sugammadex sodium Impurity 50
Cabozantinib impurity 39 Cabozantinib impurity 39
Cabozantinib impurity 53 Cabozantinib impurity 53
1-(2-chloro-2-(2,4-difluorophenyl)ethyl)-1H-1,2,4-triazole 1-(2-chloro-2-(2,4-difluorophenyl)ethyl)-1H-1,2,4-triazole 206050-24-0 C10H8ClF2N3
methyl 1-phenylethanesulfonate methyl 1-phenylethanesulfonate 883835-57-2 C9H12O3S
Doxofylline Impurity 22 Doxofylline Impurity 22
Dapoxetine impurity 61 Dapoxetine impurity 61
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