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| | Alectinib Impurity 10 Basic information |
| Product Name: | Alectinib Impurity 10 | | Synonyms: | Alectinib Impurity 10;5H-Benzo[b]carbazole-3-carbonitrile, 8-(1,4-dioxa-8-azaspiro[4.5]dec-8-yl)-9-ethyl-6,11-dihydro-6,6-dimethyl-11-oxo-;8-(1,4-Dioxa-8-azaspiro[4.5]dec-8-yl)-9-ethyl-6,11-dihydro-6,6-dimethyl-11-oxo-5H-benzo[b]carbazole-3-carbonitrile | | CAS: | 1256584-81-2 | | MF: | C28H29N3O3 | | MW: | 455.55 | | EINECS: | | | Product Categories: | | | Mol File: | 1256584-81-2.mol |  |
| | Alectinib Impurity 10 Chemical Properties |
| Boiling point | 728.3±60.0 °C(Predicted) | | density | 1.33±0.1 g/cm3(Predicted) | | pka | 13.70±0.40(Predicted) |
| | Alectinib Impurity 10 Usage And Synthesis |
| Uses | 8-(1,4-Dioxa-8-azaspiro[4.5]dec-8-yl)-9-ethyl-6,11-dihydro-6,6-dimethyl-11-oxo-5H-benzo[b]carbazole-3-carbonitrile is an intermediate used in the synthesis of Alectinib M4 metabolite (A521150), which is the major active metabolite of Alectinib. Alectinib is an anaplastic lymphoma kinase (ALK) inhibitor and is used to treat non-?small-?cell lung cancer by blocking the activity of anaplastic lymphoma kinase (ALK). |
| | Alectinib Impurity 10 Preparation Products And Raw materials |
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