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Pharmaceutical Impurity Reference Standards

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Structure Chemical Name CAS MF
5-chloro-N-(4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-yl)-6-(4-((4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-yl)carbamoyl)piperidin-1-yl)nicotinamide 5-chloro-N-(4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-yl)-6-(4-((4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-yl)carbamoyl)piperidin-1-yl)nicotinamide
Bisoprolol Impurity 53 Bisoprolol Impurity 53
Abiolone Impurity 24 Abiolone Impurity 24
Deerasirox Impurity II Deerasirox Impurity II
Brivaracetam Impurity 49 Brivaracetam Impurity 49
Paroxetine EP Impurity J HCl Paroxetine EP Impurity J HCl
Brivaracetam Impurity 99 Brivaracetam Impurity 99
Bendamustine Impurity 39 Bendamustine Impurity 39
AvatrombopagImpurity42 AvatrombopagImpurity42
(R)-4-(((R)-1-carboxy-2-((3-hydroxypropyl)thio)ethyl)amino)-3-hydroxy-4-oxobutanoic acid (R)-4-(((R)-1-carboxy-2-((3-hydroxypropyl)thio)ethyl)amino)-3-hydroxy-4-oxobutanoic acid
Hydrazinecarboxamide, 2-(6-hydroxy-1-methyl-1H-indol-5-yl)- Hydrazinecarboxamide, 2-(6-hydroxy-1-methyl-1H-indol-5-yl)- 70063-07-9 C10H12N4O2
1H-Pyrrole-3-carboxaldehyde, 1-[(5-chloro-3-pyridinyl)sulfonyl]-5-(2-fluorophenyl)- 1H-Pyrrole-3-carboxaldehyde, 1-[(5-chloro-3-pyridinyl)sulfonyl]-5-(2-fluorophenyl)- 2514742-82-4 C16H10ClFN2O3S
Crisaborole Impurity 20 Crisaborole Impurity 20
(Z)-N-(4-((3-chloro-4-fluorophenyl)amino)-7-methoxyquinazolin-6-yl)-4-(piperidin-1-yl)but-2-enamide (Z)-N-(4-((3-chloro-4-fluorophenyl)amino)-7-methoxyquinazolin-6-yl)-4-(piperidin-1-yl)but-2-enamide
(1S,3R,5S,6R)-6-hydroxy-8-methyl-8-azabicyclo[3.2.1]octan-3-yl 2-hydroxy-2,2-di(thiophen-2-yl)acetate (1S,3R,5S,6R)-6-hydroxy-8-methyl-8-azabicyclo[3.2.1]octan-3-yl 2-hydroxy-2,2-di(thiophen-2-yl)acetate
Nicergoline EP Impurity IJ Nicergoline EP Impurity IJ
Fulvestrant impurityABCDEFGHJKL Fulvestrant impurityABCDEFGHJKL
2-((6S,8S,9S,10S,11S,13S,14S,17R)-11,17-dihydroxy-6,10,13-trimethyl-3-oxohexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl acetate 2-((6S,8S,9S,10S,11S,13S,14S,17R)-11,17-dihydroxy-6,10,13-trimethyl-3-oxohexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl acetate 114696-04-7 C24H36O6
Isavuconazole Impurity 49 Isavuconazole Impurity 49
(R)-5-(2-((5,6-diethyl-2,3-dihydro-1H-inden-2-yl)amino)-1-methoxyethyl)-8-hydroxyquinolin-2(1H)-one (R)-5-(2-((5,6-diethyl-2,3-dihydro-1H-inden-2-yl)amino)-1-methoxyethyl)-8-hydroxyquinolin-2(1H)-one
Avatrombopag Impurity 51 Avatrombopag Impurity 51
Tafluprost Impurity 18 Tafluprost Impurity 18
Rosuvastatin Impurity 161 Rosuvastatin Impurity 161
Rosuvastatin Impurity 155 Rosuvastatin Impurity 155
Rosuvastatin Impurity 146 Rosuvastatin Impurity 146
Rosuvastatin Impurity 126 Rosuvastatin Impurity 126
(1R,3r,5S)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl 2-hydroxy-2,2-di(thiophen -2-yl)acetate (1R,3r,5S)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl 2-hydroxy-2,2-di(thiophen -2-yl)acetate 29461-90-3 C18H21NO3S2
Digoxin Impurity 2 Digoxin Impurity 2
DUTP, 100MM SOLUTION DUTP, 100MM SOLUTION 94736-09-1 C9H16N2NaO14P3
Oxacillin USP Impurity D Oxacillin USP Impurity D
Oxacillin sodium EP impurity B Oxacillin sodium EP impurity B
Doxylamine Impurity E Doxylamine Impurity E
Phenoxymethylpenicillin Potassium EP Impurity F Phenoxymethylpenicillin Potassium EP Impurity F 2714805-53-3 C15H20N2O4S
Methylprednisolone EP Impurity D1 Methylprednisolone EP Impurity D1
Nirmatrelvir Impurity 13 Nirmatrelvir Impurity 13
2-Pyridinecarboxamide, 4-hydroxy-N-methyl- (9CI) 2-Pyridinecarboxamide, 4-hydroxy-N-methyl- (9CI) 611226-36-9 C7H8N2O2
2-Pyridinemethanol, 4-hydroxy-3,5-dimethyl- (9CI) 2-Pyridinemethanol, 4-hydroxy-3,5-dimethyl- (9CI) 727375-13-5 C8H11NO2
Bumetanide Impurity 22 Bumetanide Impurity 22
Rocuronium Bromide Impurity 32 、33 Rocuronium Bromide Impurity 32 、33
Flucloxacillin Sodium Impurity X Flucloxacillin Sodium Impurity X
Pitavastatin Impurity 98 Pitavastatin Impurity 98
Perospirone Impurity 29 Perospirone Impurity 29
Perospirone Impurity 24 Perospirone Impurity 24
Perospirone Impurity 7 Perospirone Impurity 7
2-methyl-4-(((2E,6E,10E)-3,7,11,15-tetramethylhexadeca-2,6,10,14- tetraen-1-yl)oxy)naphthalen-1-yl acetate 2-methyl-4-(((2E,6E,10E)-3,7,11,15-tetramethylhexadeca-2,6,10,14- tetraen-1-yl)oxy)naphthalen-1-yl acetate
Paxlovid Impurity 17 Paxlovid Impurity 17
NA NA
Fondaparinux sodium impurity 16 Fondaparinux sodium impurity 16
Fondaparinux Sodium Impurity 11 Fondaparinux Sodium Impurity 11
Oxacillin Impurity E Oxacillin Impurity E
AZOBENZENE-3-CARBOXYLICACID AZOBENZENE-3-CARBOXYLICACID 14474-22-7 C13H10N2O2
Bosutinib Impurity 40 Bosutinib Impurity 40
Ticagrelor Impurity J&K Ticagrelor Impurity J&K
Olodaterol Impurity 24 Olodaterol Impurity 24
Chloromethyl ethyl carbonate Chloromethyl ethyl carbonate 35179-98-7 C4H7ClO3
Bimatoprost Impurity 10 Bimatoprost Impurity 10
Carbetocin S-Oxide II Carbetocin S-Oxide II
Empagliflozin Impurity 82 Empagliflozin Impurity 82 2452301-16-3 C17H16ClIO2
Empagliflozin Impurity 88 Empagliflozin Impurity 88
Tofacitinib Impurity K Tofacitinib Impurity K 2328165-36-0 C16H21N5O3
Olopatadine Impurity 13 Olopatadine Impurity 13 55453-90-2 C18H16O4
Avibactam sodium Impurity CIA Avibactam sodium Impurity CIA
4-((2-amino-2-oxoethyl)amino)butanoic acid 4-((2-amino-2-oxoethyl)amino)butanoic acid 1096803-44-9 C6H12N2O3
Lenvatinib impurity LFZZ-17 Lenvatinib impurity LFZZ-17 C11H9NO4
Ornidazole Impurity 25 Ornidazole Impurity 25
Pitavastatin Impurity 72 Pitavastatin Impurity 72
Febuxostat Impurity 109 Febuxostat Impurity 109
Brivaracetam Impurity 37 Brivaracetam Impurity 37
Ticagrelor Impurity 133 Ticagrelor Impurity 133
4-[(1,3-Dihydro-1-hydroxy-2,1-benzoxaborol-5-yl)oxy]-benzamide 4-[(1,3-Dihydro-1-hydroxy-2,1-benzoxaborol-5-yl)oxy]-benzamide 1187188-59-5 C14H12BNO4
2-Propenoic acid, 3-[4-(hydroxymethyl)phenyl]- 2-Propenoic acid, 3-[4-(hydroxymethyl)phenyl]- 219915-41-0 C10H10O3
L-Alanine, 3-[(R)-(carboxymethyl)sulfinyl]- L-Alanine, 3-[(R)-(carboxymethyl)sulfinyl]- 61475-35-2 C5H9NO5S
Phenol, 2-(2-phenyldiazenyl)- Phenol, 2-(2-phenyldiazenyl)- 2362-57-4 C12H10N2O
3-Quinolinecarboxylic acid, 1-cyclopropyl-7-fluoro-1,4-dihydro-6,8-dimethoxy-4-oxo- 3-Quinolinecarboxylic acid, 1-cyclopropyl-7-fluoro-1,4-dihydro-6,8-dimethoxy-4-oxo- 2410658-30-7 C15H14FNO5
Hexanoic acid, 3-(hydroxymethyl)- Hexanoic acid, 3-(hydroxymethyl)- 81381-87-5 C7H14O3
1-Pyrrolidinecarboxylic acid, 3,3'-dithiobis[5-[(dimethylamino)carbonyl]-, 1,1'-bis[(4-nitrophenyl)methyl] ester, (3S,3'S,5S,5'S)- 1-Pyrrolidinecarboxylic acid, 3,3'-dithiobis[5-[(dimethylamino)carbonyl]-, 1,1'-bis[(4-nitrophenyl)methyl] ester, (3S,3'S,5S,5'S)- 936226-36-7 C30H36N6O10S2
D-Glucitol, 1,5-anhydro-1-C-[4-chloro-3-[[4-(1-methylethoxy)phenyl]methyl]phenyl]-, (1S)- D-Glucitol, 1,5-anhydro-1-C-[4-chloro-3-[[4-(1-methylethoxy)phenyl]methyl]phenyl]-, (1S)- 946525-39-9 C22H27ClO6
Topiroxostat Impurity 42 Topiroxostat Impurity 42
Crisaborole intermediate Crisaborole intermediate 1187188-60-8 C14H13BO4
Regorafenib Impurity MHY Regorafenib Impurity MHY
2-Thiazolamine, 5-(4-cyclohexyl-1-piperazinyl)-4-(4,5-dichloro-2-thienyl)- 2-Thiazolamine, 5-(4-cyclohexyl-1-piperazinyl)-4-(4,5-dichloro-2-thienyl)- 570407-63-5 C17H22Cl2N4S2
INDEX NAME NOT YET ASSIGNED INDEX NAME NOT YET ASSIGNED 2417213-74-0 C42H42N4O12S
Lumateperone Impurity 6 Lumateperone Impurity 6 313368-82-0 C23H26FN3O
1H-?Indole-?5,?6-?diol, 1-?[3-?(4-?hydroxyphenyl)?-?1-?methylpropyl]?- 1H-?Indole-?5,?6-?diol, 1-?[3-?(4-?hydroxyphenyl)?-?1-?methylpropyl]?- 2514709-72-7 C18H19NO3
Miglitol Isomer ImpurityB Miglitol Isomer ImpurityB
benzhydryl (6R,7S)-7-(2-mercaptoacetamido)-7-methoxy-3-(((1-methyl-1H-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate benzhydryl (6R,7S)-7-(2-mercaptoacetamido)-7-methoxy-3-(((1-methyl-1H-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
43,50-Dicarboxy-cyanoco balamin 43,50-Dicarboxy-cyanoco balamin
(1R,4S) Sertraline Hydrochloride (1R,4S) Sertraline Hydrochloride 79896-32-5 C17H18Cl3N
4-Desmethoxy-4-chloro Omeprazole Sulfide 4-Desmethoxy-4-chloro Omeprazole Sulfide 220757-74-4 C16H16ClN3OS
N-Desmethyl Tamoxifen Hydrochloride N-Desmethyl Tamoxifen Hydrochloride 15917-65-4 C25H27NO.ClH
(3S,5S)-Atorvastatin sodium salt (3S,5S)-Atorvastatin sodium salt 501121-34-2 C33H35FN2O5
2(1H)-Pyrazinone, 3-phenyl- 2(1H)-Pyrazinone, 3-phenyl- 2882-18-0 C10H8N2O
1H-Thieno[3,4-d]imidazole-4-valeric acid, hexahydro-2-oxo-, stereoisomer (8CI) 1H-Thieno[3,4-d]imidazole-4-valeric acid, hexahydro-2-oxo-, stereoisomer (8CI) 21788-37-4 C10H16N2O3S
pazufloxacin pazufloxacin 166665-94-7 C16H15FN2O4
MK 485 MK 485 28875-92-5 C10H14N2O4
1,3-Dioxane-4-aceticacid,6-(cyanomethyl)-2,2-dimethyl-,(4R,6R)-(9CI) 1,3-Dioxane-4-aceticacid,6-(cyanomethyl)-2,2-dimethyl-,(4R,6R)-(9CI) 807312-27-2 C10H15NO4
bromobenzarone bromobenzarone 94729-09-6 C17H13BrO3
digoxigenin-bis(digitoxoside) digoxigenin-bis(digitoxoside) 5297-05-2 C35H54O11
17 alpha-cyanomethyl-19-nortestosterone 17 alpha-cyanomethyl-19-nortestosterone 67473-36-3 C20H27NO2
desmethylazelastine desmethylazelastine 47491-38-3 C21H22ClN3O
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