Tofacitinib Impurity K

Tofacitinib Impurity K Basic information
Product Name:Tofacitinib Impurity K
Synonyms:Azilsartan medoxomil impurity332;3-((3R,4R)-4-Methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanoic acid (Tofacitinib Impurity);1-Piperidinepropanoic acid, 4-methyl-3-(methyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-β-oxo-, (3R,4R)-
CAS:2328165-36-0
MF:C16H21N5O3
MW:331.38
EINECS:
Product Categories:
Mol File:2328165-36-0.mol
Tofacitinib Impurity K Structure
Tofacitinib Impurity K Chemical Properties
density 1.367±0.06 g/cm3(Predicted)
solubility DMSO (Slightly), Methanol (Slightly)
form Solid
pka4.96±0.32(Predicted)
color White to Off-White
Safety Information
MSDS Information
Tofacitinib Impurity K Usage And Synthesis
Uses3-((3R,4R)-4-Methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanoic Acid is an impurity of Tofacitinib (T528000), an enantiopure stereoisomer of the drug, Janus kinase 3(Jak3) inhibitor (CP-690,550) that has been found to inhibit selected members of the STE7 and STE20 subfamily of kinases.
Tofacitinib Impurity K Preparation Products And Raw materials

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