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| | Dapagliflozin-d5 Basic information |
| Product Name: | Dapagliflozin-d5 | | Synonyms: | (1S)-1,5-Anhydro-1-C-[4-chloro-3-[[4-(ethoxy-1,1,2,2,2-d5)phenyl]methyl]phenyl]-D-glucitol;Dapagliflozin-d5;[2H5]-Dapagliflozin;BMS-512148 D5;(1S)-1,5-Anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-D-glucitol-D5;2-(4-chloro-3-(4-(ethoxy-d5)benzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol;(2S,3R,4R,5S,6R)-2-(4-chloro-3-(4-(ethoxy-d5)benzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol | | CAS: | 1204219-80-6 | | MF: | C21H20ClD5O6 | | MW: | 413.90340889 | | EINECS: | | | Product Categories: | | | Mol File: | 1204219-80-6.mol |  |
| | Dapagliflozin-d5 Chemical Properties |
| Melting point | >62°C (dec.) | | storage temp. | Hygroscopic, -20°C Freezer, Under inert atmosphere | | solubility | DMSO (Slightly), Ethanol (Slightly), Methanol (Slightly) | | form | Solid | | color | White to Off-White | | Stability: | Hygroscopic |
| | Dapagliflozin-d5 Usage And Synthesis |
| Description | Dapagliflozin-d5 is a deuterium labeled Dapagliflozin. Dapagliflozin is a competitive SGLT2 inhibitor. | | Uses | Dapagliflozin-D5 is a labelled analogue of Dapagliflozin (D185370), a selective sodium-glucose cotransporter-2 inhibitor that reduces renal glucose reabsorption and is used to treat patients with type 2 diabetes. | | Uses | Labeled Dapagliflozin, Dapagliflozin-d5 can be intended for use as an internal standard for the quantification of Dapagliflozin by GC- or LC-mass spectrometry.
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| | Dapagliflozin-d5 Preparation Products And Raw materials |
| Raw materials | Ethan-1,1,2,2,2-d5-ol, 1-(4-methylbenzenesulfonate)-->((2R,3S,4R,5R,6S)-6-(4-chloro-3-(4-((S)-tetrahydrofuran-3-yloxy)benzyl)phenyl)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl)Methyl acetate-->4-(5-broMo-2-chlorobenzyl)phenol |
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