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Cibenzoline

Cibenzoline Basic information
Product Name:Cibenzoline
Synonyms:CIBENZOLINE;(RS)-Cibenzoline;1H-Imidazole, 2-(2,2-diphenylcyclopropyl)-4,5-dihydro-;Cifenline;Ro 22-7796;UP 33-901;cibenzoline:2-(2,2-diphenylcyclopropyl)-4,5-dihydro-1h-IMIDAZOLE;Cibenol
CAS:53267-01-9
MF:C18H18N2
MW:262.35
EINECS:258-453-7
Product Categories:Cifenline
Mol File:53267-01-9.mol
Cibenzoline Structure
Cibenzoline Chemical Properties
Melting point 103-104°
Boiling point 449.2±45.0 °C(Predicted)
density 1.17±0.1 g/cm3(Predicted)
storage temp. 2-8°C
solubility Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
pka10.82±0.40(Predicted)
form Solid
color White to Pale Yellow
CAS DataBase Reference53267-01-9
Safety Information
ToxicityLD100 in rats (mg/kg): 64 i.v. (Cognaco)
MSDS Information
Cibenzoline Usage And Synthesis
DescriptionCibenzoline is a structurally novel, class I (quinidine-like) antiarrhythmic agent. It has additional properties of class III and class IV compounds, delaying repolarization and antagonizing the positive inotropic effects of calcium.
OriginatorHexachemie (France)
UsesCibenzoline acts as a highly active class I antiarrhythmic agent.
UsesCardiac depressant.
DefinitionChEBI: Cibenzoline is a diarylmethane.
Brand nameCIPRALAN
Cibenzoline Preparation Products And Raw materials
Raw materialsAcrylonitrile-->Ethylenediamine-->Diphenyldiazomethane
Diphenylphosphine Cibenzoline CIBENZOLINE SUCCINATE 5-Methyl-2-phenyl-1,2-dihydropyrazol-3-one Naphazoline hydrochloride Cefazolin Diphenylmethane Diphenylsilane CYCLOPROPANECARBOXAMIDINE Chlorodiphenylphosphine Imidazole 3-METHYL-BUTYRAMIDINE Cibenzoline succinate Cefazolin sodium salt Dichlorodiphenylsilane Dihydromyrcenol 4-methylpentanimidamide tert-Butylchlorodiphenylsilane
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