SESQUITERPENE

Sesquiterpene having three isoprene units is a kind of terpene , whose general formula is CH, most of them are in line with isoprene rule. Sesquiterpene compounds widely distributed, most abundant in Magnoliales, rue mesh, cornales and asterales (asterales) plants. Generally speaking, sesquiterpene presents in volatile oil in the form of oxygen-containing derivativesthe , such as alcohols, ketones and lactones, the main composition of volatile oil in the high-boiling part , have a strong aroma and biological activity, are pharmaceutical, food, cosmetics important raw material for industry.

Sesquiterpene compounds, in terms of the number or type of structure from the point of view of the skeleton are the largest one in terpenoids. Sesquiterpene are classified by the number of  carbon ring on their structure , for example, acyclic, monocyclic, bicyclic, tricyclic and tetracyclic and so on. Also classified according to the size of the ring, such as five, six, seven till eleven membered ring. If it is classified according to containing group in its structure, it is easy to recognize their physicochemical properties and physiological activities, such as sesquiterpene alcohols, aldehydes, lactones and so on.

The following are some common sesquiterpene compound:
(1) Farnesol ,an open-chain sesquiterpene, presents in aromatic plants volatile oil such as lemongrass, orange blossom, rose and others. Farnesol as a colorless oily liquid, is a valuable spice. having insect juvenile hormone activity. Once the amount of the insect juvenile hormone excess, it will inhibit the insect metamorphosis and maturity.
(2)Germacrone, Aka Big geranylflavanone ketone, presents in the volatile oil of Xing'an azalea (rhododendron) leaves, is a ten-member ring monocyclic sesquiterpene. Rhododendron volatile oil has the effect of treating cough, phlegm, asthma and are useful for the treatment of chronic bronchitis, cuckoo ketone ,whose melting point is 56 ~ 57 ℃,is the main component .
(3) Gguaiazulene. a sesquiterpene ingredients, presents in the tribulus plants guaiac volatile oil, volatile oil Geranium.
guaiazulene. a blue needle crystallization,whose melting point is 31 ℃, has anti-inflammatory effect, promoting wound healing. It is one of the main components of  domestic burn ointment.

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Structure Chemical Name CAS MF
(-)-GLOBULOL (-)-GLOBULOL 489-41-8 C15H26O
(2S)-3α-Vinyl-3-methyl-2β-(1-methylvinyl)-6β-isopropylcyclohexanone (2S)-3α-Vinyl-3-methyl-2β-(1-methylvinyl)-6β-isopropylcyclohexanone 21698-44-2 C15H24O
VOMIFOLIOL VOMIFOLIOL 23526-45-6 C13H20O3
Tussilagone Tussilagone 104012-37-5 C23H34O5
2-O-Acetyltutin 2-O-Acetyltutin 2749-28-2 C17H20O7
(1R,8aα)-1,4aβ-Dimethyl-7β-(1-hydroxy-1-methylethyl)decalin-1α-ol (1R,8aα)-1,4aβ-Dimethyl-7β-(1-hydroxy-1-methylethyl)decalin-1α-ol 4666-84-6 C15H28O2
corianin corianin 35481-77-7 C15H18O6
Deoxy Artemisinin Deoxy Artemisinin 72826-63-2 C15H22O4
Clovanediol Clovanediol 2649-64-1 C15H26O2
(1aS,7S,7aR,8S)-1a,1b,5,6,6a,7a-Hexahydro-1bα,6β-dihydroxy-6aα-methyl-8-(1-methyl-1-hydroxyethyl)spiro[2α,5α-methano-7H-oxireno[3,4]cyclopent[1,2-d]oxepine-7,2'-oxiran]-3(2H)-one (1aS,7S,7aR,8S)-1a,1b,5,6,6a,7a-Hexahydro-1bα,6β-dihydroxy-6aα-methyl-8-(1-methyl-1-hydroxyethyl)spiro[2α,5α-methano-7H-oxireno[3,4]cyclopent[1,2-d]oxepine-7,2'-oxiran]-3(2H)-one 19417-00-6 C15H20O7
(1R,8aα)-Decahydro-1-methyl-6-methylene-4β-isopropyl-1α,4aβ-naphthalenediol (1R,8aα)-Decahydro-1-methyl-6-methylene-4β-isopropyl-1α,4aβ-naphthalenediol 25330-21-6 C15H26O2
11(13)-Dehydroivaxillin 11(13)-Dehydroivaxillin 87441-73-4 C15H20O4
Homalomel A Homalomel A 145400-03-9 C15H26O2
Onitin Onitin 53823-02-2 C15H20O3
3-O-Methyltirotundin 3-O-Methyltirotundin 1021945-29-8 C20H30O6
alismol alismol 87827-55-2 C15H24O
Brevilin A Brevilin A 16503-32-5 C20H26O5
SPATHULENOL SPATHULENOL 6750-60-3 C15H24O
(-)-EPIGLOBULOL (-)-EPIGLOBULOL 88728-58-9 C15H26O
1-acetyltagitinin A 1-acetyltagitinin A 60547-63-9 C21H30O8
Bullatantriol Bullatantriol 99933-32-1 C15H28O3
Epoxyparvilide Epoxyparvilide 102227-61-2 C15H22O3
Pterosin Z Pterosin Z 34169-69-2 C15H20O2
tirotundin tirotundin 56377-67-4 C19H28O6
3,4,4aα,5,6,7,8,8a-Octahydro-3α-hydroxy-5,5,8aβ-trimethyl-2-naphthalenecarbaldehyde 3,4,4aα,5,6,7,8,8a-Octahydro-3α-hydroxy-5,5,8aβ-trimethyl-2-naphthalenecarbaldehyde 72537-20-3 C14H22O2
2,4,6-Trihydroxy-5-[(1R)-1-[(1aβ,4R,4aβ,7aα,7bβ)-1,1,4,7-tetramethyl-4β-hydroxydecahydro-1H-cyclopropa[e]azulene-7α-yl]-3-methylbutyl]isophthalaldehyde 2,4,6-Trihydroxy-5-[(1R)-1-[(1aβ,4R,4aβ,7aα,7bβ)-1,1,4,7-tetramethyl-4β-hydroxydecahydro-1H-cyclopropa[e]azulene-7α-yl]-3-methylbutyl]isophthalaldehyde 132951-90-7 C28H40O6
4,10-Aromadendranediol 4,10-Aromadendranediol 70051-38-6 C15H26O2
Carabrolactone B Carabrolactone B 1187925-31-0 C15H22O4
Tagitinin A Tagitinin A 59979-61-2 C19H28O7
Piptocarphin A Piptocarphin A 76248-63-0 C21H26O9
roseoside roseoside 54835-70-0 C19H30O8
eucalyptone eucalyptone 172617-99-1 C28H38O7
santamarine santamarine 4290-13-5 C15H20O3
(2S,5E)-5-Methyl-9-methylene-2-isopropyl-5-cyclodecen-1-one (2S,5E)-5-Methyl-9-methylene-2-isopropyl-5-cyclodecen-1-one 25645-19-6 C15H24O
7,8-Dihydrovomifoliol 7,8-Dihydrovomifoliol 36151-01-6 C13H22O3
ASCLEPOSIDE E ASCLEPOSIDE E 325686-49-5 C19H32O8
Blumel C glucoside Blumel C glucoside 135820-80-3 C19H32O7
Xanthinin Xanthinin 153483-31-9 C17H22O5
Chlorouvedalin Chlorouvedalin 24694-80-2 C23H29ClO9
(3Z,7Z)-3,7,11-trimethyl-13-oxabicyclo[8.3.0]trideca-3,7,11,14-tetraene (3Z,7Z)-3,7,11-trimethyl-13-oxabicyclo[8.3.0]trideca-3,7,11,14-tetraene 57566-47-9 C15H20O
1,10:4,5-Diepoxy-7(11)-germacren-8-one 1,10:4,5-Diepoxy-7(11)-germacren-8-one 32179-18-3 C15H22O3
4,8-Dihydroxyeudesm-7(11)-en-12,8-olide 4,8-Dihydroxyeudesm-7(11)-en-12,8-olide 1231208-53-9 C15H22O4
5beta-Hydroxycostic acid 5beta-Hydroxycostic acid 132185-84-3 C15H22O3
9-Oxo-10,11-dehydroageraphorone 9-Oxo-10,11-dehydroageraphorone 79491-71-7 C15H20O2
Corchoiol C Corchoiol C 189351-15-3 C13H20O3
Pterodontic acid Pterodontic acid 185845-89-0 C15H22O2
Shizukaol D Shizukaol D 142279-42-3 C33H38O9
Voleneol Voleneol 70389-88-7 C15H26O2
macrocarpal J macrocarpal J 179603-47-5 C28H42O7
STACHYBOTRYLACTAM STACHYBOTRYLACTAM 163391-76-2 C23H31NO4
9-Epiblumel B 9-Epiblumel B 22841-42-5 C13H22O3
Macrocarpal K Macrocarpal K 218290-59-6 C28H40O6
Mucrolidin Mucrolidin 227471-20-7 C15H28O3
Tagitinin F Tagitinin F 59979-57-6 C19H24O6
1-[[(1S,3aα,7aβ)-Octahydro-4β-hydroxy-4-methyl-7β-isopropyl-1H-inden]-1-yl]ethanone 1-[[(1S,3aα,7aβ)-Octahydro-4β-hydroxy-4-methyl-7β-isopropyl-1H-inden]-1-yl]ethanone 1911-78-0 C15H26O2
1,7-Dihydroxy-1,6-dimethyl-4-isopropylnaphthalen-2(1H)-one 1,7-Dihydroxy-1,6-dimethyl-4-isopropylnaphthalen-2(1H)-one 41653-72-9 C15H18O3
1,4,7-Eudesmanetriol 1,4,7-Eudesmanetriol 145400-02-8 C15H28O3
1,9-Caryolanediol 9-acetate 1,9-Caryolanediol 9-acetate 155488-34-9 C17H28O3
Onitisin Onitisin 53823-03-3 C15H20O4
(1S)-1,2,3,4,4a,5,8,8aα-Octahydro-1,4aβ-dimethyl-7-isopropyl-1,4β-naphthalenediol (1S)-1,2,3,4,4a,5,8,8aα-Octahydro-1,4aβ-dimethyl-7-isopropyl-1,4β-naphthalenediol 13902-62-0 C15H26O2
(1aR,7aα,7bβ)-Decahydro-1,1,4α,7β-tetramethyl-4aH-cycloprop[e]azulen-4aα-ol (1aR,7aα,7bβ)-Decahydro-1,1,4α,7β-tetramethyl-4aH-cycloprop[e]azulen-4aα-ol 5986-49-2 C15H26O
3,6-Caryolanediol 3,6-Caryolanediol 155485-76-0 C15H26O2
3-Hydroxy-4,15-dir-1(5)-xanthen-12,8-olide 3-Hydroxy-4,15-dir-1(5)-xanthen-12,8-olide 1093207-99-8 C13H20O3
4(15),5,10(14)-Germacratrien-1-ol 4(15),5,10(14)-Germacratrien-1-ol 81968-62-9 C15H24O
9-Oxo-2,7-bisaboladien-15-oic acid 9-Oxo-2,7-bisaboladien-15-oic acid 93888-59-6 C15H22O3
Byzantioside B Byzantioside B 189109-45-3 C19H32O7
Chrysothol Chrysothol 911714-91-5 C15H26O2
Epipterosin L Epipterosin L 52611-75-3 C15H20O4
4-Oxobedfordiaic acid 4-Oxobedfordiaic acid 68799-38-2 C15H22O3
Carabrolactone A Carabrolactone A 1187925-30-9 C15H22O5
Cyclocalopin A Cyclocalopin A 486430-94-8 C15H20O6
Macrocarpal D Macrocarpal D 142647-71-0 C28H40O6
reynosin reynosin 28254-53-7 C15H20O3
(2R,8aβ)-Decahydro-8β-hydroxy-4aα,8-dimethyl-α-methylene-2-naphthaleneacetic acid (2R,8aβ)-Decahydro-8β-hydroxy-4aα,8-dimethyl-α-methylene-2-naphthaleneacetic acid 4586-68-9 C15H24O3
(S)-6-[2-(β-D-Glucopyranosyloxy)ethyl]-2,3-dihydro-3-hydroxy-2,2,5,7-tetramethyl-1H-inden-1-one (S)-6-[2-(β-D-Glucopyranosyloxy)ethyl]-2,3-dihydro-3-hydroxy-2,2,5,7-tetramethyl-1H-inden-1-one 35943-38-5 C21H30O8
(1aR,4E,7R,7aR,10aS,10bR)-7-Acetoxy-2,3,6,7,7a,8,10a,10b-octahydro-1a,5-dimethyl-8-methyleneoxireno[9,10]cyclodeca[1,2-b]furan-9(1aH)-one (1aR,4E,7R,7aR,10aS,10bR)-7-Acetoxy-2,3,6,7,7a,8,10a,10b-octahydro-1a,5-dimethyl-8-methyleneoxireno[9,10]cyclodeca[1,2-b]furan-9(1aH)-one 41059-80-7 C17H22O5
1,7-Diepi-8,15-cedranediol 1,7-Diepi-8,15-cedranediol 40768-81-8 C15H26O2
8-Hydroxy-4-cadinen-3-one 8-Hydroxy-4-cadinen-3-one 97372-53-7 C15H24O2
9-Oxoageraphorone 9-Oxoageraphorone 105181-06-4 C15H22O2
Cucumegastigmane I Cucumegastigmane I 929881-46-9 C13H20O4
Sulfocostulide B Sulfocostulide B 1059671-65-6 C15H20O5S
Teuclatriol Teuclatriol 152110-17-3 C15H28O3
Dendocarbin A Dendocarbin A 350986-74-2 C15H22O3
2,3-Dihydroxypterodontic acid 2,3-Dihydroxypterodontic acid 185821-32-3 C15H22O4
2-Desoxy-4-epi-pulchellin 2-Desoxy-4-epi-pulchellin 122872-03-1 C15H22O3
4-Cadinen-7-ol 4-Cadinen-7-ol 217650-27-6 C15H26O
5alpha-Hydroxycostic acid 5alpha-Hydroxycostic acid 132185-83-2 C15H22O3
Kobusone Kobusone 24173-71-5 C14H22O2
Macrocarpal C Macrocarpal C 142628-53-3 C28H38O5
Macrocarpal N Macrocarpal N 221899-21-4 C28H38O7
O-Acetylcyclocalopin A O-Acetylcyclocalopin A 486430-93-7 C17H22O7
Pterodondiol Pterodondiol 60132-35-6 C15H28O2
Shizukaol C Shizukaol C 142279-41-2 C36H42O10
Viteralone Viteralone 87440-75-3 C15H14O3
Clovanediol diacetate Clovanediol diacetate 2649-68-5 C19H30O4
enantio-7(11)-Eudesmen-4-ol enantio-7(11)-Eudesmen-4-ol 186374-63-0 C15H26O
Guajadial Guajadial 959860-49-2 C30H34O5
Isocostic acid Isocostic acid 69978-82-1 C15H22O2
Macrocarpal E Macrocarpal E 142628-54-4 C28H40O6
Methyl isodrimenil Methyl isodrimenil 442851-27-6 C16H26O2
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