Antiamoebic and anti-trichomoniasis drugs

Antiamoebic drug is mainly used for the treatment of amoebae disease caused by the dissolved tissue amoebae. Amoeba parasitize in the human intestinal in two basic forms--trophozoites and cysts. Infectious amebic cysts are contagious. After being swallowed, trophozoites broken out of the capsule, living in the intestinal life, melting tissue and penetrating into the submucosal tissue within the division of reproduction, leading to intestinal wall ulcers, and causing acute or chronic amoebic dysentery. If the environment is not suitable, the trophozoites will become cyst with thick cystic wall; excrete with the feces, and then infect the new host. Amoebic trophozoites sometimes migrate to the liver, lung and brain tissue to stay breeding with the intestinal wall blood flow, and cause liver abscess, lung abscess and brain abscess, known as parenteral amoebiasis. At present, the majority of anti-amoebic drugs can kill trophozoites; a small number of drugs kill cysts. In addition, some antibiotics such as paromomycin, oxytetracycline can kill the trophozoites or inhibit symbiotic flora to treat amibiasis.
Trichomoniasis is a disease mainly caused by trichomonas vaginitis and the vaginal flagellum trichomoniasis, which can also be parasitic in the male genitourinary tract, spreading through sexual contact. At present, metronidazole is the the most effective drugs to treat vaginal trichomoniasis, and anti-metronidazole trichomoniasis infection can also use acetyl arsenic amine, trichostatin to cure.