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| | cilengitide Basic information |
| Product Name: | cilengitide | | Synonyms: | 2-[(2S,5R,8S,11S)-5-benzyl-11-[3-(diaminomethylideneamino)propyl]-7-methyl-3,6,9,12,15-pentaoxo-8-propan-2-yl-1,4,7,10,13-pentazacyclopentadec-2-yl]acetic acid;Cyclo(L-arginylglycyl-L-aspartyl-D-phenylalanyl-N-methyl-L-valyl);Cilengitide(EMD121974,NSC-707544);Cilengitide;C(RGDf-Me-V);EMD 121974;EMD-121974;EMD121974;CS-1500;CS-2674 | | CAS: | 188968-51-6 | | MF: | C27H40N8O7 | | MW: | 588.66 | | EINECS: | | | Product Categories: | Inhibitors | | Mol File: | 188968-51-6.mol |  |
| | cilengitide Chemical Properties |
| density | 1.41±0.1 g/cm3(Predicted) | | storage temp. | -20°C | | solubility | ≥29.43 mg/mL in DMSO; ≥22.56 mg/mL in H2O | | form | powder | | pka | 4.01±0.10(Predicted) | | color | white to beige | | Water Solubility | Soluble to 10 mg/ml in water |
| | cilengitide Usage And Synthesis |
| Uses | Angiogenesis
inhibitor. | | Uses | Cilengitide trifluoroacetic acid salt has been used as an inhibitor of integrin αvβ5. | | Definition | ChEBI: Cilengitide is an oligopeptide. | | Biochem/physiol Actions | It exhibits antitumor activity in glioblastoma multiforme tumors. Integrins are heterodimers of α and β chain. They are transmembrane receptors which are responsible for cell-to-cell and cell-extracellular matrix interactions. They control tumor angiogenesis, invasion and migration. | | storage | Store at -20°C |
| | cilengitide Preparation Products And Raw materials |
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