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| | HYDROQUINIDINE Basic information |
| Product Name: | HYDROQUINIDINE | | Synonyms: | (1S)-((2R,4S,5R)-5-ethylquinuclidin-2-yl)(6-Methoxyquinolin-4-yl)Methanol;aluminum triacetate;Dihydroquinidine,99%d.e.;(S)-((1S,2R,4S,5R)-5-ethylquinuclidin-2-yl)(6-methoxyquinolin-4-yl)methanol;Quinine Sulphate Impurity 1;(9s)-10,11-dihydro-6’-methoxycinchonan-9-ol;(9S)-10,11-Dihydro-6'-methoxycinchonan-9-ol;10,11-Dihydroquinidine | | CAS: | 1435-55-8 | | MF: | C20H26N2O2 | | MW: | 326.43 | | EINECS: | 215-862-5 | | Product Categories: | Inhibitors | | Mol File: | 1435-55-8.mol |  |
| | HYDROQUINIDINE Chemical Properties |
| Melting point | 169-170 °C(lit.) | | alpha | 226 º (C=2 IN ETOH) | | Boiling point | 464.47°C (rough estimate) | | density | 1.1117 (rough estimate) | | refractive index | 1.6800 (estimate) | | storage temp. | Keep in dark place,Sealed in dry,Room Temperature | | solubility | chloroform: 0.1 g/mL, clear | | pka | 12.80±0.20(Predicted) | | form | A crystalline solid | | optical activity | [α]25/D +226°, c = 2 in ethanol | | Merck | 13,4831 | | BRN | 91441 | | InChIKey | LJOQGZACKSYWCH-LHFMAAMQSA-N | | CAS DataBase Reference | 1435-55-8(CAS DataBase Reference) | | NIST Chemistry Reference | Hydroquinidine(1435-55-8) |
| Hazard Codes | Xn | | Risk Statements | 20/21/22 | | Safety Statements | 36/37-36 | | RIDADR | 1544 | | WGK Germany | 3 | | RTECS | MX3016000 | | HazardClass | 6.1(b) | | PackingGroup | III | | HS Code | 29339900 |
| | HYDROQUINIDINE Usage And Synthesis |
| Chemical Properties | Solid | | Uses | antiarrhythmic, antimalarial | | Purification Methods | It is slightly soluble in Et2O and H2O but readily soluble in hot EtOH. [Heidelberger & Jacobs J Am Chem Soc 41 826 1919, King J Chem Soc 523 1946.] The hydrochloride has m 273-274o, [] 26D +184o (c 1.3, MeOH) and is very soluble in MeOH and CHCl3, but less soluble in H2O, EtOH and still less soluble in dry Me2CO. [Kyker & Lewis J Biol Chem 157 707 1945, Emde Helv Chim Acta 15 557 1932, Beilstein 23/13 V 340.] |
| | HYDROQUINIDINE Preparation Products And Raw materials |
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