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| | Demethyl-Coclaurine Basic information |
| Product Name: | Demethyl-Coclaurine | | Synonyms: | Demethyl-Coclaurine;DL-Demethylcoclaurine;Norcoclaurine;1-(4-hydroxybenzyl)-1,2,3,4-tetrahydroisoquinoline-6,7-diol;1-[(4-hydroxyphenyl)methyl]-1,2,3,4-tetrahydroisoquinoline-6,7-diol;1,2,3,4-Tetrahydro-1-[(4-hydroxyphenyl)methyl]-6,7-isoquinolinediol;1-(4-Hydroxybenzyl);(RS)-norcoclaurine | | CAS: | 5843-65-2 | | MF: | C16H17NO3 | | MW: | 271.31 | | EINECS: | | | Product Categories: | Anilines, Aromatic Amines and Nitro Compounds | | Mol File: | 5843-65-2.mol |  |
| | Demethyl-Coclaurine Chemical Properties |
| Melting point | 208-210 °C | | Boiling point | 522.4±50.0 °C(Predicted) | | density | 1.317±0.06 g/cm3(Predicted) | | storage temp. | Refrigerator | | solubility | DMSO (Slightly), Methanol (Slightly) | | form | Solid | | pka | 9.72±0.40(Predicted) | | color | White to Off-White |
| | Demethyl-Coclaurine Usage And Synthesis |
| Uses | (±)-Norcoclaurine can be used to prevent and treat of Alzheimer’s disease, bind to SARS-CoV-2 S protein:human ACE2 complex, as a bronchodilator to improve lung function in various respiratory diseases, and an antioxidant in lipid-like environments. It can also be used as a racemic salt-acidic compound to produce elevated and sustained ketosis. | | Uses | Demethyl-Coclaurine acts through inhibition of middle cerebral artery occlusion (MCAO)-mediated HMGB1 release in vivo. Useful towards ischemic injuries.
| | Definition | ChEBI: (RS)-norcoclaurine is a norcoclaurine. It is a conjugate base of a (RS)-norcoclaurinium. |
| | Demethyl-Coclaurine Preparation Products And Raw materials |
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