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| 4-Acetylpyridine Basic information |
| 4-Acetylpyridine Chemical Properties |
Melting point | 13-16 °C(lit.) | Boiling point | 212 °C(lit.) | density | 1.095 g/mL at 25 °C(lit.) | refractive index | n20/D 1.529(lit.) | Fp | >230 °F | storage temp. | Inert atmosphere,Room Temperature | solubility | Chloroform, Ethyl Acetate | pka | pK1: 3.505(+1) (25°C) | form | Liquid | color | brown-yellowish | Specific Gravity | 1.110 (20/4℃) | Water Solubility | insoluble | BRN | 107629 | InChIKey | WMQUKDQWMMOHSA-UHFFFAOYSA-N | LogP | 0.480 | CAS DataBase Reference | 1122-54-9(CAS DataBase Reference) | NIST Chemistry Reference | Ethanone, 1-(4-pyridinyl)-(1122-54-9) | EPA Substance Registry System | 4-Acetylpyridine (1122-54-9) |
| 4-Acetylpyridine Usage And Synthesis |
Chemical Properties | clear light yellow to brownish liquid | Uses | 4-Acetylpyridine is a acetylated pyridine used in the preparation of nitrogen containing bicyclic heterocycles and other organic compounds. 4-Acetylpyridine is also present in mainstream cigarette smo
ke. | Uses | 4-acetylpyridine on reaction with - and 4-formylpyridine (H3FoPyS, H4FoPyS) yields semicarbazones. Reaction of acetylpyridine with thiophene-2-carboxaldehyde afforded the 2-chloro-6-ethoxy-4-β-(2-thienyl)acryloylpyridine, which was reacted with malononitrile in refluxing ethanol in the presence of piperidine as a catalyst to afford the cyanoaminopyrane derivative. | General Description | Dark amber liquid. | Air & Water Reactions | Soluble in water. | Reactivity Profile | 4-Acetylpyridine is incompatible with strong oxidizing agents and strong reducing agents. . Amines are chemical bases. They neutralize acids to form salts plus water. These acid-base reactions are exothermic. The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides. | Fire Hazard | 4-Acetylpyridine is probably combustible. |
| 4-Acetylpyridine Preparation Products And Raw materials |
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