2-Methyl-D-phenylalanine

2-Methyl-D-phenylalanine Basic information
Product Name:2-Methyl-D-phenylalanine
Synonyms:N-ME-D-PHENYLALANINE;N-ME-D-PHE-OH;N-METHYL-D-PHENYLALANINE;(R)-2-METHYLPHENYLALANINE;(R)-2-AMINO-2-METHYL-3-PHENYLPROPANOIC ACID;(R)-2-AMINO-2-METHYL-3-PHENYLPROPIONIC ACID;N-ALPHA-METHYL-D-PHENYLALANINE;ALPHA-BENZYL-D-ALA
CAS:17350-84-4
MF:C10H13NO2
MW:179.22
EINECS:
Product Categories:α-Methyl Amino Acids;unnatural amino acids;Unusual amino acids;pharmacetical;Chiral Reagent
Mol File:17350-84-4.mol
2-Methyl-D-phenylalanine Structure
2-Methyl-D-phenylalanine Chemical Properties
Melting point 277-279 °C(Solv: acetone (67-64-1))
Boiling point 312.8±30.0 °C(Predicted)
density 1.166±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
pka2.25±0.10(Predicted)
form Powder
color White to pale yellow
BRN 5254151
CAS DataBase Reference17350-84-4(CAS DataBase Reference)
Safety Information
Hazard Codes Xn
Risk Statements 22
WGK Germany 3
MSDS Information
2-Methyl-D-phenylalanine Usage And Synthesis
Chemical PropertiesWhite powder
Usesα-Methyl-D-phenylalanine is used to prepare hippuryl-α-methylphenylalanine and hippuryl-α-methylphenyllactic acid as substrates for carboxypeptidase A. It is also used in the synthesis of high affinity tachykinin NK2 receptor antagonists.
Uses2-Methyl-D-phenylalanine is a derivative of D-Phenylalanine (P319410); the stereoisomer of L-Phenylalanine (P319415) used in the synthesis of Schaeffer’s acid analogs as important structures in tuberculostatic design. These analogs exhibit the ability to inhibit Mycobacterium tuberculosis type II dehydroquinase.
2-Methyl-D-phenylalanine Preparation Products And Raw materials
Methylparaben 2-Methyl-D-phenylalanine Α-METHYL-DL-PHENYLALANINE β-Alanine Methyl L-Phenylalanine Bensulfuron methyl Isobutyric acid DL-Phenylalanine (-)-ALPHA-[HYDROXYMETHYL]TYROSINE Glycine Dichloromethylphenylsilane Dimethylaminobenzaldehyde Kresoxim-methyl DIETHYL 2-(ACETYLAMINO)-2-[4-(METHOXYMETHYL)BENZYL]MALONATE DIETHYL 2-(ACETYLAMINO)-2-[4-(METHOXYCARBONYL)BENZYL]MALONATE 2-AMINOINDAN-2-CARBOXYLIC ACID HYDROCHLORIDE Tris(hydroxymethyl)aminomethane

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