ChemicalBook Product Catalog Analytical Chemistry Standard Pharmaceutical Impurity Reference Standards D(-)-AMETHOPTERIN

D(-)-AMETHOPTERIN

D(-)-AMETHOPTERIN Basic information
Product Name:D(-)-AMETHOPTERIN
Synonyms:d-methotrexate;n-(4-(((2,4-diamino-6-pteridinyl)methyl)methylamino)benzoyl)-d-glutamicacid;D(-)-AMETHOPTERIN;D-(-)-AMETHOPTERIN HYDRATE;D(-)-4-AMINO-N10-METHYLPTEROYLGLUTAMIC ACID;D-(-)-N-(2,4-diamino-6-pteridinyl(dimethylamino)benzoyl)glutamic acid;R-Methotrexate (5 mg) ((R)-2-(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)amino}benzamido)pentanedioic acid);R-Methotrexate
CAS:51865-79-3
MF:C20H22N8O5
MW:454.44
EINECS:257-482-2
Product Categories:
Mol File:51865-79-3.mol
D(-)-AMETHOPTERIN Structure
D(-)-AMETHOPTERIN Chemical Properties
Melting point 195 °C
Boiling point 561.26°C (rough estimate)
density 1.4080 (rough estimate)
refractive index 1.6910 (estimate)
storage temp. -20°C
solubility Aqueous Base (Slightly, Heated, Sonicated), DMSO (Slightly), Methanol (Slightly）
pka3.47±0.10(Predicted)
form Solid
color Dark Yellow to Very Dark Yellow
Stability:Hygroscopic
Safety Information
Hazard Codes T
Risk Statements 61-46-25-36/37/38-60-23/24/25
Safety Statements 53-45-28A-36/37/39-26-22
RIDADR UN 1544 6.1/PG 3
RTECS MA1224000
HS Code 29335995
MSDS Information
ProviderLanguage
ACROS English
D(-)-AMETHOPTERIN Usage And Synthesis
Chemical PropertiesSolid
UsesR-Methotrexate is an enantiomer of Methotrexate (M260675), a folic acid antagonist. Used as a antineoplastic and antirheumatic.
D(-)-AMETHOPTERIN Preparation Products And Raw materials
4-[Methyl[(2-amino-4-hydroxypteridine)-6-ylmethyl]amino]benzoic acid L-Glutamic acid, N-[4-[[ (2-amino-1, 4-dihydro-4-oxo-6-pteridinyl)meth yl]methylamino]benzoyl]- 2,4-DIAMINO-6-(HYDROXYMETHYL)PTERIDINE Methotrexate EP Impurity G N-(4-(METHYLAMINO)BENZOYL)-L-GLUTAMIC ACID Aminopterin Methotrexate Related Compound E (50 mg) (4-{[(2,4-Diaminopteridin-6-yl)methyl](methyl)amino}benzoic acid, hemihydrochloride) D-AMETHOPTERIN HYDRATE, 95 (+)-Amethopterin-methyl-d3, 4-Amino-10-methylpteroylglutamic-methyl-d3 Acid 7-Hydroxy Amethopterin, 4-Amino-7-hydroxy-10-methylpteroylglutamic Acid 7-Hydroxy Amethopterin-d3 4-Amino-7-hydroxy-10-methylpteroylglutamic Acid-d3 DL-AMETHOPTERIN HYDRATE L-AMETHOPTERIN HYDRATE,L-(+)-AMETHOPTERIN HYDRATE,(+)-AMETHOPTERIN HYDRATE Methotrexate L(+)-AMETHOPTERIN DIHYDRATE D(-)-AMETHOPTERIN HYDRATE, 98 (plus-minus)-amethopterin,dl-amethopteri
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