1-PHENYL-3-BUTEN-1-OL

1-PHENYL-3-BUTEN-1-OL Basic information
Product Name:1-PHENYL-3-BUTEN-1-OL
Synonyms:1-PHENYL-3-BUTEN-1-OL;1-PHENYL-3-BUTENE-1-OL;4-PHENYL-1-BUTEN-4-OL;α-(2-Propenyl)bennzyl alcohol;α-(2-Propenyl)benzenemethanol;α-Allylbenzenemethanol;α-Allylbenzyl alcohol;4-Phenyl-1-buten-4-ol,97%
CAS:936-58-3
MF:C10H12O
MW:148.21
EINECS:
Product Categories:Acyclic;Alkenes;Organic Building Blocks
Mol File:936-58-3.mol
1-PHENYL-3-BUTEN-1-OL Structure
1-PHENYL-3-BUTEN-1-OL Chemical Properties
Boiling point 234 °C (lit.)
density 0.992 g/mL at 25 °C (lit.)
refractive index n20/D 1.53(lit.)
Fp 217 °F
pka14.22±0.20(Predicted)
form Liquid
color Clear colorless
Safety Information
WGK Germany 2
HS Code 29062900
MSDS Information
ProviderLanguage
ACROS English
SigmaAldrich English
1-PHENYL-3-BUTEN-1-OL Usage And Synthesis
Chemical Propertiesclear colorless liquid
Uses4-Phenyl-1-buten-4-ol is a building block that can be used in the synthesis of (R)-2,3-Dihydro-2-phenyl-4H-1-benzopyran-4-one (H447850), which is an impurity of Propafenone (P757500), a sodium channel blocker and an antiarrhythmic (class IC) compound.
DefinitionChEBI: 1-phenyl-3-buten-1-ol is an aromatic alcohol that is (but-3-en-1-yl)benzene in which one of the benzylic methylene hydrogens has been replaced by a hydroxy group. It is a secondary alcohol, an aromatic alcohol and an olefinic compound.
Synthesis Reference(s)Chemistry Letters, 17, p. 2049, 1988
Journal of the American Chemical Society, 110, p. 4473, 1988 DOI: 10.1021/ja00221a091
Tetrahedron Letters, 30, p. 5413, 1989 DOI: 10.1016/S0040-4039(01)80581-5
1-PHENYL-3-BUTEN-1-OL Preparation Products And Raw materials
(Z)-3,4-Diphenyl-4-[4-[2-(dimethylamino)ethoxy]phenyl]-3-buten-1-ol (E)-1-(p-Tolylsulfinyl)-4-phenyl-3-buten-2-ol 4-(4-METHYOXY)PHENYL-1-BUTEN-4-OL 97,4-(4-METHOXY)PHENYL-1-BUTEN-4-OL 97% (E)-2-Methyl-4-phenyl-3-buten-2-ol 1-PHENYL-3-BUTEN-1-OL ACETATE 2,2-Dimethyl-1-phenyl-3-buten-1-ol 3-Ethylthio-2-phenyl-3-buten-2-ol (1S)-1-Phenyl-3-buten-1-ol [R,E,(+)]-4-Phenyl-3-buten-2-ol,[2R,3E,(+)]-4-Phenyl-3-buten-2-ol 1-PHENYL-2-BUTEN-1-OL 1-PHENYL-3-BUTEN-1-OL,4-PHENYL-1-BUTEN-4-OL 1-[4-(1-Hydroxy-3-butenyl)phenyl]-3-buten-1-ol 4-(Trimethylsilyl)-4-(phenylthio)-1-phenyl-3-buten-1-ol 1-PHENYL-1-BUTEN-3-OL ACETATE 4-phenyl-3-buten-2-ol ,TRANS-4-PHENYL-3-BUTEN-2-OL 4-Phenyl-3-buten-1-ol 3-Methyl-1-phenyl-3-buten-1-ol (1S,2S)-2-Methyl-1-phenyl-3-buten-1-ol

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