Albiflorin

Albiflorin Basic information
Product Name:Albiflorin
Synonyms:(1R,3R,4R,6S,9S)-9-[(Benzoyloxy)Methyl]-1-(beta-D-glucopyranosyloxy)-4-hydroxy-6-Methyl-7-oxatricyclo[4.3.0.03,9]nonan-8-one;Albiflorin, froM Paeonia lactiflora;ALBIFLORIN;Albiflorin 9-((Benzoyloxy)methyl)-1-(beta-D-glucopyranosyloxy)-4-hydroxy-6-methyl-7-oxatricyclononan-8-one;Albiflorin std;9-((Benzoyloxy)methyl)-1-(beta-D-glucopyranosyloxy)-4-hydroxy-6-methyl-7-oxatricyclononan-8-one;[(benzoyloxy)methyl]-1-(β-D-glucopyranosyloxy)-;4-hydroxy-6-methyl-, (1R, 3R, 4R, 6S)-
CAS:39011-90-0
MF:C23H28O11
MW:480.46
EINECS:
Product Categories:The group of Paeoniflorin;Miscellaneous Natural Products;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract
Mol File:39011-90-0.mol
Albiflorin Structure
Albiflorin Chemical Properties
Boiling point 722.1±60.0 °C(Predicted)
density 1.58±0.1 g/cm3(Predicted)
storage temp. Keep in dark place,Inert atmosphere,2-8°C
solubility DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 30 mg/ml; PBS (pH 7.2): 10 mg/ml
form powder
pka12.84±0.70(Predicted)
color White
Safety Information
Safety Statements 24/25
WGK Germany 3
HS Code 29389090
MSDS Information
Albiflorin Usage And Synthesis
DefinitionChEBI: Albiflorin is a monoterpene glycoside with formula C23H28O11, originally isolated from the roots of Paeonia lactiflora. It has a role as a plant metabolite and a neuroprotective agent. It is a benzoate ester, a gamma-lactone, a beta-D-glucoside, a monoterpene glycoside, a secondary alcohol and a bridged compound.
Biological FunctionsAlbiflorin is a natural product isolated from Paeoniae Radix. It enhances mitochondrial function to suppress antimycin A-induced oxidative damage via the preservation of cytochrome c and cardiolipin. Also it may reduce or prevent osteoblast degeneration in osteoporosis.
Biological ActivityAlbiflorin is a natural phenolic compound that has been shown to be an inhibitor of toll-like receptor (TLR) 4.
in vitroAlbiflorin can modulate the TLR-induced inflammatory response by inhibiting the production of proinflammatory cytokines, such as IL-6, IL-8, and TNF-α. This compound also inhibits matrix metalloproteinase activity in tubulointerstitial injury, leading to decreased interstitial inflammation and proteinuria. Albiflorin has been shown to be effective at low doses in experimental models of rheumatoid arthritis. It is believed that this effect may be due to its ability to inhibit TLR4 expression or activation.
Albiflorin Preparation Products And Raw materials
Paeoniflorin Methylparaben Paraquat dichloride METHYL CYCLOBUTANECARBOXYLATE Methyl Acetonitrile N-(2,6-dichloro-3-methyl-phenyl)-2-(3,4-dimethylphenyl)sulfanyl-acetamide 2-METHYL CYCLOBUTANECARBOXYLIC ACID ALPHA,ALPHA-DIMETHYL-GAMMA-BUTYROLACTONE Cyclobutanecarboxylic acid Basic Violet 1 Kresoxim-methyl Cyclobutanol Methanol Methyl acrylate CHLOROPHOSPHONAZO III Albiflorin Spironolactone

Email:[email protected] [email protected]
Copyright © 2024 Mywellwork.com All rights reserved.