1-Bromo-2,4,5-trifluorobenzene

1-Bromo-2,4,5-trifluorobenzene Basic information
Product Name:1-Bromo-2,4,5-trifluorobenzene
Synonyms:2,4,5-Trifluorobromobenzene 99%;1-BROMO-2,4,5-TRIFLUOROBENZENE;2,4,5-TRIFLUOROBENZOBROMIDE;2,4,5-TRIFLUOROBROMOBENZENE;2-BROMO-1,4,5-TRIFLUOROBENZENE;Two, four, five, three fluorine broMobenzene;2,4,5 bromobenzene;1-Bromo-2,4,5-trifluorobenzene 99%
CAS:327-52-6
MF:C6H2BrF3
MW:210.98
EINECS:206-318-8
Product Categories:Benzenes;Aryl;Aromatic Hydrocarbons (substituted) & Derivatives;Miscellaneous;C6;Halogenated Hydrocarbons
Mol File:327-52-6.mol
1-Bromo-2,4,5-trifluorobenzene Structure
1-Bromo-2,4,5-trifluorobenzene Chemical Properties
Melting point −19 °C(lit.)
Boiling point 144 °C(lit.)
density 1.802 g/mL at 25 °C(lit.)
refractive index n20/D 1.485(lit.)
Fp 132 °F
storage temp. 2-8°C
solubility water: insoluble
form clear liquid
Specific Gravity1.81
color Colorless to Light yellow to Light orange
Water Solubility insoluble
BRN 1636588
CAS DataBase Reference327-52-6(CAS DataBase Reference)
NIST Chemistry ReferenceBenzene, 1-bromo-2,4,5-trifluoro-(327-52-6)
Safety Information
Hazard Codes Xi,F
Risk Statements 36/37/38-10
Safety Statements 26-36/37/39-37/39-16
RIDADR UN 1993 3/PG 3
WGK Germany 3
Hazard Note Flammable
HazardClass 3
PackingGroup III
HS Code 29039990
MSDS Information
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1-Bromo-2,4,5-trifluorobenzene Usage And Synthesis
Chemical Propertiesclear slightly yellow liquid
Uses1-Bromo-2,4,5-trifluorobenzene is the intermediate of liquid crystals. The derivatives of this compound can be used as intermediates for the synthesis of qunolone antibacterial. It is employed in the synthesis of 3-ethenyl, 3-ethynyl, 3-aryl, and 3-cyclopropyl-2, 4, 5-trifluorobenzoic acids from 1-bromo-2, 4, 5-trifluorobenzene and 2, 4, 5-trifluoro-3-hydroxybenzoic acid.
UsesIntermediates of Liquid Crystals
DefinitionChEBI: 1-Bromo-2,4,5-trifluorobenzene is an organofluorine compound.
General Description1-Bromo-2,4,5-trifluorobenzene undergoes Br-Mg-exchange reaction with i-PrMgBr in THF to yield organomagnesium compound.
1-Bromo-2,4,5-trifluorobenzene Preparation Products And Raw materials
Preparation Products2,4,5-Trifluorophenylacetic acid-->(R)-3-AMino-4-(2,4,5-trifluoro-phenyl)-butyric acid hydrochloride-->Sitagliptin N-Boc IMpurity-->Carbamic acid, N-[(1R)-3-hydroxy-1-[(2,4,5-trifluorophenyl)methyl]propyl]-, 1,1-dimethylethyl ester
2-BROMO-1,3,4-TRIFLUOROBENZENE,1-Bromo-2,3,6-trifluorobenzene 98%,1-Bromo-2,3,6-trifluorobenzene98% 1-Bromo-2,3,5-trifluorobenzene98%,1-Bromo-2,3,5-trifluorobenzene 98%,1-BROMO-2,3,5-TRIFLUOROBENZENE 1,2,4-TRIFLUOROBENZENE OR 1-BROMO 2,4,5-TRIFLUOROBENZENE 1-BROMO-2,3,6-TRIFLUOROBENZENE 1-Bromo-2,4,6-trifluorobenzene 2,3,4-Trifluorobromobenzene 5-BROMO-1,2,3-TRIFLUOROBENZENE,1-BROMO-3,4,5-TRIFLUOROBENZENE,1-Bromo-3,4,5-trifluorobenzene99%,1-Bromo-3,4,5-trifluorobenzene 99%

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