METHYL PHENYL SULFOXIDE

METHYL PHENYL SULFOXIDE Basic information
Product Name:METHYL PHENYL SULFOXIDE
Synonyms:Sulfoxide, methyl phenyl;Thioanisole S-oxide;METHYL PHENYL SULFOXIDE;(methylsulphinyl)benzene;METHYL PHENYL SULFOXIDE, 97+%;Methyl phenyl sulfoxide, 98+%;Benzene, (methylsulfinyl)-;Methyl phenyl sulphoxide, 98+%
CAS:1193-82-4
MF:C7H8OS
MW:140.2
EINECS:214-781-2
Product Categories:Sulfur Compounds;Sulfur Compounds (for Synthesis);Synthetic Organic Chemistry;Organic Building Blocks;Sulfoxides
Mol File:1193-82-4.mol
METHYL PHENYL SULFOXIDE Structure
METHYL PHENYL SULFOXIDE Chemical Properties
Melting point 26-29 °C (lit.)
Boiling point 139-140 °C/14 mmHg (lit.)
density 1.1182 (rough estimate)
refractive index n20/D 1.5775(lit.)
Fp 187 °F
storage temp. 2-8°C
form Crystalline Low Melting Mass
color White
Sensitive Hygroscopic
BRN 1904976
CAS DataBase Reference1193-82-4(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Risk Statements 37/38-41
Safety Statements 22-24/25-39-26
WGK Germany 3
HS Code 29309090
MSDS Information
ProviderLanguage
ACROS English
SigmaAldrich English
ALFA English
METHYL PHENYL SULFOXIDE Usage And Synthesis
Chemical Propertieswhite crystalline low melting mass
UsesMethyl phenyl sulfoxide has been used in the synthesis of:
  • isotopically labelled 1, 3-dithiane, a useful labeled synthon
  • nelfinavir, potent HIV-protease inhibitor
  • sulfoximines and in studies on solvent-water partitioning
DefinitionChEBI: (methylsulfinyl)benzene is a sulfoxide resulting from the formal oxidation of the sulfur atom of thioanisole. It is a sulfoxide and a member of benzenes. It is functionally related to a thioanisole.
Synthesis Reference(s)The Journal of Organic Chemistry, 50, p. 2847, 1985 DOI: 10.1021/jo00216a007
Tetrahedron Letters, 22, p. 4591, 1981 DOI: 10.1016/S0040-4039(01)82989-0
General Description(R)-methyl phenyl sulfoxide is an important pharmaceutical intermediate.
2,4-bis(methylsulphonyl)phenylhydrazine 4-HEXADECYLSULFONYLANILINE REACTIVE BLACK 5 (6-CHLORO-2-METHYL-4-PYRIMIDINYL)METHYL PHENYL SULFOXIDE Sulfenone Phenyl vinyl sulfone METHYL (PHENYLSULFINYL)ACETATE (6-MORPHOLINO-2-PHENYL-4-PYRIMIDINYL)METHYL PHENYL SULFOXIDE 2-(Phenylsulfonyl)aniline PHENYL VINYL SULFOXIDE [4-(Methylsulfonyl)phenyl]hydrazine hydrochloride 2-AMINO-5-(4-NITROPHENYLSULFONYL)THIAZOLE 1-BROMOMETHYL-2-[(PHENYLSULFONYL)METHYL]BENZENE DIBENZOTHIOPHENE SULFONE 4-CHLOROPHENYL 2-CHLORO-1,1,2-TRIFLUOROETHYL SULFONE 4-CHLOROPHENYL SULFOXIDE 4,4'-Dichlorodiphenyl sulfone 2,6-dichloro-4-mesylaniline

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