ChemicalBook Product Catalog Organic Chemistry Amides Acyclic polyamines and their derivatives 4-Methylaniline hydrochloride

4-Methylaniline hydrochloride

4-Methylaniline hydrochloride Basic information
Product Name:4-Methylaniline hydrochloride
Synonyms:p-Toluidine hydrochlori;4-methylaniliniumchloride;4-methylbenzenaminehydrochloride;4-methyl-benzenaminhydrochloride;p-Toluidine hydrochloride purum, >=99.0% (AT);p-Toluidinium chloride for synthesis;4-TOLUIDINE HYDROCHLORIDE;4-AMINO-1-METHYLBENZENE HYDROCHLORIDE
CAS:540-23-8
MF:C7H10ClN
MW:143.61
EINECS:208-740-8
Product Categories:Nitrogen Compounds;Organic Building Blocks;Amine Salts;Building Blocks;Chemical Synthesis
Mol File:540-23-8.mol
4-Methylaniline hydrochloride Structure
4-Methylaniline hydrochloride Chemical Properties
Melting point 243-245 °C(lit.)
density 1.193 g/cm3
storage temp. Store below +30°C.
Water Solubility Soluble in water
solubility DMSO (Sparingly), Methanol (Slightly)
form powder to crystal
color White to Gray to Red
BRN 3557540
Stability:Hygroscopic
CAS DataBase Reference540-23-8(CAS DataBase Reference)
EPA Substance Registry Systemp-Toluidine hydrochloride (540-23-8)
Safety Information
Hazard Codes T,N
Risk Statements 23/24/25-36-40-43-50
Safety Statements 28-36/37-45-61
RIDADR UN 2811 6.1/PG 1
WGK Germany 3
RTECS XU7525000
HazardClass 6.1(a)
PackingGroup II
HS Code 29214300
MSDS Information
ProviderLanguage
SigmaAldrich English
ACROS English
4-Methylaniline hydrochloride Usage And Synthesis
Chemical Propertieswhite to light beige crystalline powder, crystals
Usesp-Toluidine Hydrochloride acts as a reagent for the preparation and biological activity of N-acylleucine (arylaminoethyl)amides as non-covalent inhibitors of cathepsin K, L and S. Catalyst in the chemistry of azasteroids.
General DescriptionOff-white to grayish-white crystals.
Air & Water ReactionsWater soluble. May be sensitive to moisture.
Reactivity Profile4-Methylaniline hydrochloride reacts with oxidizing and alkali materials. .
Fire HazardFlash point data for 4-Methylaniline hydrochloride are not available, but 4-Methylaniline hydrochloride is probably combustible.
Safety ProfilePoison by intraperitoneal route. Moderately toxic by ingestion. Questionable carcinogen with experimental carcinogenic and tumorigenic data. When heated to decomposition it emits very toxic fumes of NOx and HCl. See also p-TOLUIDINE.
Purification MethodsCrystallise the salt from MeOH containing a few drops of conc HCl or aqueous EtOH. Dry it under vacuum over paraffin chips. [Beilstein 12 II 587, 12 III 2021, 12 IV 1869.]
4-Methylaniline hydrochloride Preparation Products And Raw materials
Preparation Products3,5-Dibromotoluene-->3,5-DIBROMO-4-IODOTOLUENE-->2,6-Dibromo-4-methylaniline-->AKOS BBS-00005699
DIPHENYLAMINE HYDROCHLORIDE Basic Red 9 Aniline hydrochloride N-Methylaniline N-METHYL-P-TOLUIDINE 3,3',5,5'-Tetramethylbenzidine dihydrochloride Topotecan hydrochloride Sibutramine hydrochloride N,N-Dimethyl-p-toluidine toluidine 3,3'-Dimethylbenzidine dihydrochloride Basic Blue 17 N,N-Dimethylaniline 4-Hydroxyaniline hydrochloride o-Toluidine 1-AdaMantanethylaMine p-Toluidine 2-Chloro-4-nitrotoluene
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