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| N-(tert-Butoxycarbonyl)-L-alanine Basic information |
| N-(tert-Butoxycarbonyl)-L-alanine Chemical Properties |
Melting point | 79-83 °C(lit.) | alpha | -26 º (c=2, acetic acid) | Boiling point | 324.46°C (rough estimate) | density | 1.2321 (rough estimate) | refractive index | -25.5 ° (C=2, AcOH) | storage temp. | Sealed in dry,2-8°C | solubility | DMSO, Methanol | pka | 4.02±0.10(Predicted) | form | Granular Powder | color | White | optical activity | [α]20/D 25±1°, c = 2% in acetic acid | BRN | 1726365 | CAS DataBase Reference | 15761-38-3(CAS DataBase Reference) | EPA Substance Registry System | L-Alanine, N-[(1,1-dimethylethoxy)carbonyl]- (15761-38-3) |
| N-(tert-Butoxycarbonyl)-L-alanine Usage And Synthesis |
Chemical Properties | White to off-white microcrystalline powder | Uses | Boc-Ala-OH can be used:
- In the preparation of N-propargylalanine, a key precursor to generate N-(3-aryl)propylated alanine residues.
- In the resolution of racemic mixture of 3,3′-bis(benzyloxy)-1,1′-binaphthalene-2,2′-diol.
- In the one-pot synthesis of hybrid tripeptidomimetics containing both amide and imide functionalities.
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| N-(tert-Butoxycarbonyl)-L-alanine Preparation Products And Raw materials |
Raw materials | 4-Mercaptophenol-->TERT-BUTYL 1,2,2,2-TETRACHLOROETHYL CARBONATE)-->BOC-ALA-OTBU-->BOC-L-ALANINE METHYL ESTER-->tert-Butanol-->L-Alanine-->tert-butyl azidoformate | Preparation Products | CYCLO(-ALA-ALA)-->Carbamic acid, acetyl-, 1,1-dimethylethyl ester (9CI)-->(S)-4-Methyl-2,5-oxazolidonedione-->(S)-tert-Butyl 1-oxo-1-(2-(pyridin-2-yl)hydrazinyl)propan-2-ylcarbamate-->Carbamic acid, [2-[bis(phenylmethyl)amino]-1-methyl-2-oxoethyl]-, 1,1-dimethylethyl ester, (S)- (9CI)-->Carbamic acid, N-[(1S)-2-(3-methoxyphenyl)-1-methyl-2-oxoethyl]-, 1,1-dimethylethyl ester-->Carbamic acid, N-[(1S,2R)-2-hydroxy-2-(3-methoxyphenyl)-1-methylethyl]-, 1,1-dimethylethyl ester-->BOC-THIONOALA-1-(6-NITRO)BENZOTRIAZOLIDE-->Carbamic acid, N-[2-(methoxymethylamino)-1-methyl-2-oxoethyl]-, 1,1-dimethylethyl ester |
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