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| 2,3,5-Triphenyltetrazolium chloride Basic information |
| 2,3,5-Triphenyltetrazolium chloride Chemical Properties |
Melting point | 250 °C(lit.) | Boiling point | 490.96°C (rough estimate) | density | 1.1704 (rough estimate) | refractive index | 1.6110 (estimate) | storage temp. | 2-8°C | solubility | H2O: may be clear to slightly hazy | form | powder | color | faint yellow | Water Solubility | Soluble in water, ethanol and acetone. Insoluble in ether. | λmax | 247 nm | Sensitive | Light Sensitive & Hygroscopic | Merck | 14,9744 | BRN | 3923356 | Stability: | Stable. Light sensitive. Protect from moisture. Incompatible with strong oxidizing agents. | Biological Applications | Algae viability assay; microbial growth assays; transketolase activity screening assays; detecting bacteria,g-hydroxybutyric acid (GHB),microorganisms,myocardial infarction; measuring dehydrogenase activity; treating cancer | InChIKey | PKDBCJSWQUOKDO-UHFFFAOYSA-M | CAS DataBase Reference | 298-96-4(CAS DataBase Reference) | EPA Substance Registry System | 2,3,5-Triphenyltetrazolium chloride (298-96-4) |
Hazard Codes | Xi,Xn | Risk Statements | 36/37/38-20/21/22 | Safety Statements | 26-36 | WGK Germany | 3 | RTECS | XF8100000 | F | 3-8-10 | TSCA | Yes | HS Code | 29339900 | Toxicity | LD50 intravenous in mouse: 5600ug/kg |
| 2,3,5-Triphenyltetrazolium chloride Usage And Synthesis |
Chemical Properties | white powder | Uses | In analytical chemistry as a sensitive reagent for reducing sugars, and to distinguish between a-ketols and simple aldehydes. For staining plant and animal tissue. Germination indicator in testing the ability of seeds to germinate: G. Lakon, Ber. Dtsch. Bot. Ges. 60, 299, 434 (1942). In histochemical studies. In determination of antibiotics; of dehydrogenases. | Uses | 2,3,5-Triphenyl-2H-tetrazolium chloride is used as a dye in cell biological studies. | Uses | 2,3,5-Triphenyltetrazolium chloride is a selective serotonin 5-HT4 receptor agonist and 5-HT3 gastrointestinal prokinetic agent for functional dyspepsia
| Definition | ChEBI: An organic chloride salt having 2,3,5-triphenyltetrazolium as the counterion. | General Description | 2,3,5-Triphenyltetrazolium chloride is a colorless water-soluble dye. In the mitochondria of living cells, it is reduced to a deep red, water-insoluble compound (formazan). 2,3,5-Triphenyltetrazolium chloride helps to distinguish between viable and infarcted brain tissue after stroke. | Purification Methods | Crystallise TTZ from EtOH or CHCl3, and dry it at 105o. [Beilstein 26 H 363, 26 II 216, 26 III/IV 1774.] |
| 2,3,5-Triphenyltetrazolium chloride Preparation Products And Raw materials |
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