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Nicergoline EP Impurity G

Nicergoline EP Impurity G Basic information
Product Name:Nicergoline EP Impurity G
Synonyms:Nicergoline EP Impurity G;Ergoline-8-methanol, 1,6-dimethyl-, 8-(5-bromo-3-pyridinecarboxylate), (8β)-;8b-(5-Bromonicotinoyloxymethyl)-1,6-dimethyl-10a-ergoline;((6aR,9R,10aR)-4,7-dimethyl-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinolin-9-yl)methyl 5-bromonicotinate;(6aR,9R,10aR)-4,7-dimethyl-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinolin-9-yl]methyl 5-bromopyridine-3-carboxylate;Dihydroniergoline
CAS:57935-65-6
MF:C23H24BrN3O2
MW:454.37
EINECS:
Product Categories:
Mol File:57935-65-6.mol
Nicergoline EP Impurity G Structure
Nicergoline EP Impurity G Chemical Properties
Boiling point 583.8±45.0 °C(Predicted)
density 1.50±0.1 g/cm3(Predicted)
pka7.56±0.20(Predicted)
Safety Information
MSDS Information
Nicergoline EP Impurity G Usage And Synthesis
Uses10-Demethoxy Nicergoline is an impurity of Nicergoline (N394550) which is a drug used for age-dependent cognitive impairment such as Alzheimers disease and other types of dementia. Nicergoline has shown to protect cultured neurons against β-amyloid toxicity. Nicergoline protects against neuronal cell death induced by activated microglia and astrocytes through the inhibition of inflammatory mediators and the upregulation of neurotrophic factors by glial cells. Nicergoline is a drug used for age-dependent cognitive impairment and it protects cultured neurons against β-amyloid toxicity.
Nicergoline EP Impurity G Preparation Products And Raw materials
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