N-Ethyl-p-toluenesulfonamide

N-Ethyl-p-toluenesulfonamide Basic information
Product Name:N-Ethyl-p-toluenesulfonamide
Synonyms:Benzenesulfonamide, N-ethyl-4-methyl-;Ethyl toluenesulfonamide;Ethylp-toluenesulfonamide;n-ethyl-4-methyl-benzenesulfonamid;n-ethyl-4-methylbenzenesulfonamide;N-Ethyl-4-methyl-benzenesulfonamide;N-Ethyltoluene-4-sulfonamide for synthesis;Brinzolamide Impurity 1
CAS:80-39-7
MF:C9H13NO2S
MW:199.27
EINECS:201-275-1
Product Categories:Nitrogen Compounds;Organic Building Blocks;Protected Amines
Mol File:80-39-7.mol
N-Ethyl-p-toluenesulfonamide Structure
N-Ethyl-p-toluenesulfonamide Chemical Properties
Melting point 63-65 °C(lit.)
Boiling point 208 °C745 mm Hg(lit.)
density 1.26 g/cm3
refractive index 1.5270 (estimate)
storage temp. Sealed in dry,Room Temperature
solubility Chloroform (Slightly), Methanol (Slightly)
pka11.86±0.50(Predicted)
form Solid
color White to Off-White
Stability:Stable. Incompatible with strong oxidizing agents.
LogP1.960 (est)
CAS DataBase Reference80-39-7(CAS DataBase Reference)
NIST Chemistry Reference4-Toluenesulfonamide, n-ethyl-(80-39-7)
EPA Substance Registry SystemN-Ethyl-p-toluenesulfonamide (80-39-7)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36/37
WGK Germany 3
TSCA Yes
HS Code 29350090
MSDS Information
ProviderLanguage
N-Ethyl-p-toluenesulfonamide English
SigmaAldrich English
N-Ethyl-p-toluenesulfonamide Usage And Synthesis
Chemical Propertiesoff-white crystalline solid
UsesPlasticizer.
UsesN-Ethyl-4-toluene sulfonamide is a resin carrier in dental materials used for isolating cavities below restorations; plasticizer in polyvinyl alcohollacquers, polyamides, cellulose acetate, etc.
UsesN-?Ethyl-?p-?toluenesulfonamide is a reagent used in the sulfonamidation of imidazopyridines.
General DescriptionPlatelets (from dilute alcohol or ligroin) or off-white solid.
Air & Water ReactionsInsoluble in water.
Reactivity ProfileAn amide. Organic amides/imides react with azo and diazo compounds to generate toxic gases. Flammable gases are formed by the reaction of organic amides/imides with strong reducing agents. Amides are very weak bases (weaker than water). Imides are less basic yet and in fact react with strong bases to form salts. That is, they can react as acids. Mixing amides with dehydrating agents such as P2O5 or SOCl2 generates the corresponding nitrile. The combustion of these compounds generates mixed oxides of nitrogen (NOx).
Fire HazardFlash point data for N-Ethyl-p-toluenesulfonamide are not available; however, N-Ethyl-p-toluenesulfonamide is probably combustible.
N-Ethyl-p-toluenesulfonamide Preparation Products And Raw materials
Raw materialsEthyl acetate-->Sodium bicarbonate-->Tosyl chloride-->Ethylamine
Preparation ProductsBenzenesulfonamide, N-ethyl-2,4-dimethyl--->N-(2,2-Dimethoxyethyl)-4-methylbenzenesulfonamide
N-Ethyl-o/p-toluenesulfonamide Toluenesulfonamide N,N-Diethylhydroxylamine Ethanol Methanesulfonamide Benzenesulfonamide Ethylbenzene Ethylparaben CHLOROETHANE Tosylmethyl isocyanide Tosyl azide Ethyl cellulose Sulfanilamide Diethyl ether Ethyl acetate p-Toluenesulfonamide Ethyl acrylate N-Ethyl-p-toluenesulfonamide

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