ChemicalBook Product Catalog Pharmaceutical intermediates Bulk Drug Intermediates 2-(1-Adamantyl)-4-bromophenol

2-(1-Adamantyl)-4-bromophenol

2-(1-Adamantyl)-4-bromophenol Basic information
Product Name:2-(1-Adamantyl)-4-bromophenol
Synonyms:2-(1-Adamantyl)-4-bromophenol (Adapalene);2-(1-Adamantyl)-4-br;4-BROMO-2-ADAMANTYL PHENOL;2-(2-adamantyl)-4-bromophenol;(2-ADAMANTYL)-4-BROMOPHENOL;2-(1-ADAMANTYL)-4-BROMOPHENOL;2-(Adamantan-1-yl)-4-bromophenol;2-ADAMANTANE-4-BROMOANISOLE
CAS:104224-68-2
MF:C16H19BrO
MW:307.23
EINECS:
Product Categories:Adamantane derivatives;Phenol&Thiophenol&Mercaptan;blocks;Bromides;APIs Intermediate
Mol File:104224-68-2.mol
2-(1-Adamantyl)-4-bromophenol Structure
2-(1-Adamantyl)-4-bromophenol Chemical Properties
Melting point 137-141
Boiling point 392.0±35.0 °C(Predicted)
density 1.442±0.06 g/cm3(Predicted)
storage temp. Inert atmosphere,Room Temperature
pka9.56±0.43(Predicted)
CAS DataBase Reference104224-68-2(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Hazard Note Irritant
HS Code 2907290090
MSDS Information
2-(1-Adamantyl)-4-bromophenol Usage And Synthesis
Chemical PropertiesWhite powder
Uses2-(Adamantan-1-yl)-4-bromophenol is an intermediate in the synthesis of Adapalene (A225000), a retinoid selective for retinoic acid receptor (RAR) subtypes β and γ; an antiacne agent.
2-(1-Adamantyl)-4-bromophenol Preparation Products And Raw materials
Preparation Products1-(5-Bromo-2-methoxy-phenyl)adamantane
1-Bromo-3-n-hexylbenzene, 97+% 2-Adamantyl-4-bromo-1-(2,2,2-trifluoroethoxy)benzene 4-(1-ADAMANTYL)-2-BROMOPHENOL Adamantane 4-Bromoanisole 1-(5-Bromo-2-methoxy-phenyl)adamantane Bromophenol Blue bromophenol Adapalene 4-Bromophenol 1-[2-(Benzyloxy)-5-bromophenyl]adamantane 1-Phenyladamantane 2-(1-Adamantyl)-4-bromophenol 1-BROMO-3-TERT-BUTYLBENZENE 3-Bromophenol
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