Ezetimibe (RSS)-Isomer

Ezetimibe (RSS)-Isomer Basic information
Product Name:Ezetimibe (RSS)-Isomer
Synonyms:(3S,4S)-1-(4-fluorophenyl)-3-((R)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one;(3S,4S,3'R)-Ezetimibe;Ezetimibe (RSS)-Isomer;Ezetimibe impurities 6;Ezetimibe Impurity T;Ezetimibe-24;Ezetimibe impuriry 23/ Ezetimibe (3S,4S,3’R)-Isomer/(3S,4S)-1-(4-fluorophenyl)-3-((R)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one;Ezetimibe (3S,4R,3'R)-Isomer
CAS:1478664-18-4
MF:C24H21F2NO3
MW:409.43
EINECS:
Product Categories:
Mol File:1478664-18-4.mol
Ezetimibe (RSS)-Isomer Structure
Ezetimibe (RSS)-Isomer Chemical Properties
Boiling point 654.9±55.0 °C(Predicted)
density 1.334±0.06 g/cm3(Predicted)
pka9.72±0.30(Predicted)
Safety Information
MSDS Information
Ezetimibe (RSS)-Isomer Usage And Synthesis
Uses(3S,4S,3''R)-Ezetimibe is derived from (3S,4S)-1-(4-Fluorophenyl)-3-[3-(4-fluorophenyl)-3-oxopropyl]-4-(4-hydroxyphenyl)-2-azetidinone (F595055), which is an intermediate in the synthesis of (3S,4S,3’S)-Ezetimbe (E975040), which is a 3-epimer impurity of Ezetimibe (E975000), a cholesterol absorption inhibitor.
Ezetimibe (RSS)-Isomer Preparation Products And Raw materials
5-(4-FLUOROPHENYL)VALERIC ACID ent-EzetiMibe EzetiMibe (3R,4R,3'S)-IsoMer (R)-3-((S)-5-(4-fluorophenyl)-5-hydroxypentanoyl)-4-phenyloxazolidin-2-one (3R,4R)-1-(4-fluorophenyl)-3-((R)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one (4S)-3-(2,2-dimethylpropanoyl)-4-phenyl-1,3-oxazolidin-2-one 4-BENZOYLBUTYRIC ACID 5-(2-FLUOROPHENYL)-5-OXOVALERIC ACID 3-O-Acetyl Ezetimibe Ezetimibe Impurity 72 N-(4-(Benzyloxy)benzylidene)-4-fluoroaniline Ezetimibe Impurity 38 Ezetimibe Impurity 79 (3R,4S)-1-(4-Fluorophenyl)-2-oxo-4-[4-(benzyloxy)phenyl]-3-azetidinepropanoic acid 3-[5-(1,5-Dioxo-5-(p-fluophenylpentyl]-4R-phenyl-2-oxazolidinone EzetiMibe Fluoro IsoMer EzetiMibe LactaM Cleaved Alcohol (3S,4S)-1-(4-fluorophenyl)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one

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