ChemicalBook Product Catalog Biochemical Engineering Amino Acids and Derivatives FMOC-amino acid FMOC-7-AMINO-HEPTANOIC ACID

FMOC-7-AMINO-HEPTANOIC ACID

FMOC-7-AMINO-HEPTANOIC ACID Basic information
Product Name:FMOC-7-AMINO-HEPTANOIC ACID
Synonyms:7-Aminoheptanoic acid, N-FMOC protected;7-(FMOC-AMINO)HEPTANOIC ACID 98+%;7-(Fmoc-amino)enanthic acid, 7-(Fmoc-amino)heptanoic acid;FMoc-7-AMinoheptanoic acid FMoc-7-AMinoheptanoic acid;N-Fmoc-7-amino-heptanoic acid;7-[N-(9-Fluorenylmethoxycarbonyl)amino]heptanoic acid;Fmoc-7-aminoheptanoic acid≥ 98% (HPLC);N-(9-FLUORENYLMETHOXYCARBONYL)-7-AMINOENANTHIC ACID
CAS:127582-76-7
MF:C22H25NO4
MW:367.44
EINECS:
Product Categories:Unusual amino acids
Mol File:127582-76-7.mol
FMOC-7-AMINO-HEPTANOIC ACID Structure
FMOC-7-AMINO-HEPTANOIC ACID Chemical Properties
Boiling point 590.0±33.0 °C(Predicted)
density 1.191±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,2-8°C
pka4.77±0.10(Predicted)
form Powder
color White
Water Solubility Slightly soluble in water.
CAS DataBase Reference127582-76-7(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
WGK Germany 3
HazardClass IRRITANT
HS Code 2924297099
MSDS Information
ProviderLanguage
SigmaAldrich English
FMOC-7-AMINO-HEPTANOIC ACID Usage And Synthesis
DescriptionFmoc-7-amino-heptanoic acid is an alkane chian with terminal Fmoc-protected amine and carboxylic acid groups. The compound can be used as a PROTAC linker in the synthesis of PROTACs. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.
Chemical PropertiesWhite powder
Uses7-(Fmoc-amino)heptanoic acid is used as pharmaceutical intermediates.
FMOC-7-AMINO-HEPTANOIC ACID Preparation Products And Raw materials
FMOC-2-AMINOBICYCLO[2.2.1]HEPTANE-2-CARBOXYLIC ACID FMOC-ASU-OH (1R,2R)-FMOC-2-AMINOCYCLOHEXANE CARBOXYLIC ACID RARECHEM GF HD C015 FMOC-D-2-AMINOSUBERIC ACID FMOC-3-EXO-AMINOBICYCLO[2.2.1]HEPTANE-2-EXO-CARBOXYLIC ACID FMOC-1,2-TRANS-ACHC-OH 2-(2-TERT-BUTOXYCARBONYLAMINO-2-CARBOXY-ETHYL)-PYRROLIDINE-1-CARBOXYLIC ACID 9H-FLUOREN-9-YLMETHYL ESTER (R)-(1-FMOC-PIPERIDIN-2-YL)-ACETIC ACID (1S,2S)-FMOC-2-AMINOCYCLOHEXANE CARBOXYLIC ACID (2S,6S,9S)-FMOC-6-AMINO-2-CARBOXYMETHYL-3,8-DIAZABICYCLO-[4,3,0]-NONANE-1,4-DIONE Pyrrolo[1,2-a]pyrazine-3-acetic acid, 7-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]octahydro-1,4-dioxo-, (3S,7S,8aS)- (9CI) 4-(1-FMOC-PIPERIDIN-4-YL)-BUTYRIC ACID (1S,2R)-FMOC-2-AMINOCYCLOHEXANE CARBOXYLIC ACID FMOC-7-AMINO-HEPTANOIC ACID FMOC-3-ENDO-AMINOBICYCLO[2.2.1]HEPTANE-2-ENDO-CARBOXYLIC ACID FMOC-1,2-CIS-ACHC-OH RARECHEM AK ML 0244
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