(alphaS)-alpha-[(4-Morpholinylacetyl)aMino]benzenebutanoyl-L-leucyl-L-phenylalanine Chemical Properties
Melting point
>200°C (dec.)
Boiling point
865.6±65.0 °C(Predicted)
density
1.190±0.06 g/cm3(Predicted)
storage temp.
Sealed in dry,Store in freezer, under -20°C
solubility
DMSO (Slightly), Methanol (Slightly)
pka
3.50±0.10(Predicted)
form
Solid
color
White to Off-White
Safety Information
MSDS Information
(alphaS)-alpha-[(4-Morpholinylacetyl)aMino]benzenebutanoyl-L-leucyl-L-phenylalanine Usage And Synthesis
Uses
(S)-2-((S)-4-Methyl-2-((S)-2-(2-morpholinoacetamido)-4-phenylbutanamido)pentanamido)-3-phenylpropanoic Acid is an intermediate for Carfilzomib (C183460), which is a second-generation proteasome inhibitor that is used as a treatment in relapsed and refractory multiple myeloma.
(alphaS)-alpha-[(4-Morpholinylacetyl)aMino]benzenebutanoyl-L-leucyl-L-phenylalanine Preparation Products And Raw materials