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EzetiMibe IMpurity 1

EzetiMibe IMpurity 1 Basic information
Product Name:EzetiMibe IMpurity 1
Synonyms:EzetiMibe IMpurity 1;(3'S,3R,4S)-Desfluoro EzetiMibe;EzetiMibe IMpurity 1 ((3'S,3R,4S)-Desfluoro EzetiMibe);(3R,4S)-1-(4-fluorophenyl)-3-((S)-3-hydroxy-3-phenylpropyl)-4-(4-hydroxyphenyl)azetidin-2-one;Ezetimibe Desfluorobenzene Analog;(3R,4S)-1-(4-fluorophenyl)-3-((S);Ezetimibe-6;Ezetimibe impuriry 8/(3’S,3R,4S)-Desfluoro Ezetimibe/(3R,4S)-1-(4-fluorophenyl)-3-((S)-3-hydroxy-3-phenylpropyl)-4-(4-hydroxyphenyl)azetidin-2-one
CAS:190595-66-5
MF:C24H22FNO3
MW:391.43
EINECS:
Product Categories:Aromatics, Heterocycles, Impuities, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals
Mol File:190595-66-5.mol
EzetiMibe IMpurity 1 Structure
EzetiMibe IMpurity 1 Chemical Properties
Melting point >55°C (dec.)
Boiling point 655.0±55.0 °C(Predicted)
density 1.293±0.06 g/cm3(Predicted)
storage temp. Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility Chloroform (Slightly), Dichloromethane (Slightly), DMSO (Slightly)
pka9.72±0.30(Predicted)
form Solid
color White to Off-White
Stability:Hygroscopic
Safety Information
MSDS Information
EzetiMibe IMpurity 1 Usage And Synthesis
Uses(3’S,3R,4S)-Desfluoro Ezetimibe is an impurity of the cholesterol absorption inhibitor Ezetimibe (E975000).
EzetiMibe IMpurity 1 Preparation Products And Raw materials
EzetiMibe (3R,4R,3'S)-IsoMer (R)-3-((S)-5-(4-fluorophenyl)-5-hydroxypentanoyl)-4-phenyloxazolidin-2-one (4S)-3-(2,2-dimethylpropanoyl)-4-phenyl-1,3-oxazolidin-2-one 5-(2-FLUOROPHENYL)-5-OXOVALERIC ACID N-(4-(Benzyloxy)benzylidene)-4-fluoroaniline (4S)-3-[5-(4-Fluorophenyl)-1,5-dioxopenyl]-4-phenyl-2-oxazolidinone EzetiMibe Dehydoxy IMpurity (3R,4S)-1-(4-chlorophenyl)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one (S)-3-((2R,5S)-5-(4-fluorophenyl)-2-((S)-(4-fluorophenylaMino)(4-hydroxyphenyl)Methyl)-5-hydroxypentanoyl)-4-phenyloxazolidin-2-one (3R,4S)-1-(3-fluorophenyl)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one Ezetimibe Impurity 55 (3R,4S)-1-(4-Fluorophenyl)-2-oxo-4-[4-(benzyloxy)phenyl]-3-azetidinepropanoic acid (2R,3R,6S)-N,6-Bis(4-fluorophenyl)tetrahydro-2-(4-hydroxyphenyl)-2H-pyran-3-carboxaMide 3-[5-(1,5-Dioxo-5-(p-fluophenylpentyl]-4R-phenyl-2-oxazolidinone Methyl (3R,4S)-1-(4-fluorophenyl)-2-oxo-4-[4-(phenylmethoxy)phenyl]-3-azetidinepropanoate EzetiMibe Fluoro IsoMer (3R,4S)-1-(4-fluorophenyl)-3-((S)-3-hydroxy-3-(p-tolyl)propyl)-4-(4-hydroxyphenyl)azetidin-2-one (R)-3-((R)-5-(4-fluorophenyl)-5-hydroxypentanoyl)-4-phenyloxazolidin-2-one
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