ChemicalBook Product Catalog Biochemical Engineering Inhibitors protein tyrosine kinase CNX-2006

CNX-2006

CNX-2006 Basic information
Product Name:CNX-2006
Synonyms:CNX-2006;N-[3-[[2-[[4-[[1-(2-Fluoroethyl)-3-azetidinyl]aMino]-2-Methoxyphenyl]aMino]-5-(trifluoroMethyl)-4-pyriMidinyl]aMino]phenyl]-2-propenaMide;2-Propenamide, N-[3-[[2-[[4-[[1-(2-fluoroethyl)-3-azetidinyl]amino]-2-methoxyphenyl]amino]-5-(trifluoromethyl)-4-pyrimidinyl]amino]phenyl]-;N-[3-({2-[(4-{[1-(2-Fluoroethyl)-3-azetidinyl]amino}-2-methoxyphe nyl)amino]-5-(trifluoromethyl)-4-pyrimidinyl}amino)phenyl]acrylam ide;CS-1000;CNX2006; CNX 2006;N-(3-((2-((4-((1-(2-Fluoroethyl)azetidin-3-yl)amino)-2-methoxyphenyl)amino)-5-(trifluoromethyl)pyrimidin-4-yl)amino)phenyl)acrylamide;CNX 2006 N-[3-[[2-[[4-[[1-(2-Fluoroethyl)-3-azetidinyl]amino]-2-methoxyphenyl]amino]-5-(trifluoromethyl)-4-pyrimidinyl]amino]phenyl]-2-propenamide
CAS:1375465-09-0
MF:C26H27F4N7O2
MW:545.53
EINECS:
Product Categories:Inhibitors;Aromatics, Agonist, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals
Mol File:1375465-09-0.mol
CNX-2006 Structure
CNX-2006 Chemical Properties
density 1.396±0.06 g/cm3(Predicted)
storage temp. Store at -20° C
solubility DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2) (1:2): 0.33 mg/ml; Ethanol: 10 mg/ml
form A crystalline solid
pka13.23±0.70(Predicted)
Safety Information
MSDS Information
CNX-2006 Usage And Synthesis
UsesN-[3-[[2-[[4-[[1-(2-Fluoroethyl)-3-azetidinyl]amino]-2-methoxyphenyl]amino]-5-(trifluoromethyl)-4-pyrimidinyl]amino]phenyl]-2-propenamide, is a novel irreversible mutant-selective EGFR inhibitor.
CNX-2006 Preparation Products And Raw materials
BEZ235 (NVP-BEZ235, Dactolisib) AZD-9291 Afatinib Birinapant CO-1686 ACY-1215
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