(16α)-16,17-[Butylidenebis(oxy)]-21-hydroxypregna-1,4-diene-3,11,20-trione

(16α)-16,17-[Butylidenebis(oxy)]-21-hydroxypregna-1,4-diene-3,11,20-trione Basic information
Product Name:(16α)-16,17-[Butylidenebis(oxy)]-21-hydroxypregna-1,4-diene-3,11,20-trione
Synonyms:(16α)-16,17-[Butylidenebis(oxy)]-21-hydroxypregna-1,4-diene-3,11,20-trione;11-Keto Budesonide;Budesonide IMpurity L (11-Keto Budesonide, Mixture of DiastereoMers);11-Keto Budesonide (Mixture of DiastereoMers);16α,17-[(1RS)-butylidenebis(oxy)]-21-hydroxypregna-1,4-diene-3,11,20-trione;Budesonide EP Impurity L;Budesonide Impurity 12(Budesonide EP Impurity L);Budesonide EP Impurity L (11-Keto Budesonide) (Mixture of Diastereomers)
CAS:216453-74-6
MF:C25H32O6
MW:428.52
EINECS:
Product Categories:Impurities, Pharmaceuticals, Intermediates & Fine Chemicals, Steroids
Mol File:216453-74-6.mol
(16α)-16,17-[Butylidenebis(oxy)]-21-hydroxypregna-1,4-diene-3,11,20-trione Structure
(16α)-16,17-[Butylidenebis(oxy)]-21-hydroxypregna-1,4-diene-3,11,20-trione Chemical Properties
Melting point >97°C (dec.)
Boiling point 601.7±55.0 °C(Predicted)
density 1.27±0.1 g/cm3(Predicted)
storage temp. -20°C Freezer, Under inert atmosphere
solubility Chloroform (Slightly), Dichloromethane (Slightly), Methanol (Slightly)
pka12.83±0.10(Predicted)
form Solid
color White to Light Yellow
Safety Information
HS Code 2937290000
MSDS Information
(16α)-16,17-[Butylidenebis(oxy)]-21-hydroxypregna-1,4-diene-3,11,20-trione Usage And Synthesis
Uses11-Keto Budesonide is an impurity of Budesonide (B689490), an antiinflammatory agent.
Uses11-Keto Budesonide (Budesonide EP Impurity L) is an impurity of Budesonide (B689490), an antiinflammatory agent.
(16α)-16,17-[Butylidenebis(oxy)]-21-hydroxypregna-1,4-diene-3,11,20-trione Preparation Products And Raw materials
16α,17-[(1RS)-Butylidenebis(oxy)]-11β-hydroxy-17-(hydroxyMethyl)-D-hoMoandrosta-1,4-diene-3,17a-dione (Mixture of DiastereoMers) 9α-BroMobudesonide Budesonide 14,15-Dehydro Budesonide 21-Dehydro Budesonide Budesonide Impurity 7 21-Acetoxy-11-oxo-16α,17α-propylMethylenedioxpregna-1,4-diene-3,20-dione Di-Norbudesonide (Mixture of DiastereoMers) (11β,16α)-21-(Acetyloxy)-11,16,17-trihydroxypregna-1,4,14-triene-3,20-dione Pregna-1,4-diene-3,20-dione, 21-(acetyloxy)-9,11-epoxy-16,17-dihydroxy-, (9β,11β,16α)- Desonide 9,11-Anhydrobudesonide 16α-Butyloxyprednisolone (Budenoside IMpurity) BUDESONIDE-D8 11a,16b,17,21-Tetrahydroxy-pregna-1,4-diene-3,20-dione 21-Acetoxy-11β-hydroxy-16α,17α-propylmethylenedioxpregna-1,4-diene-3,20-dione 1,2-Dehydrobudesonide Budesonide-d6

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