NeMadipine B

NeMadipine B Basic information
Product Name:NeMadipine B
Synonyms:NeMadipine B;Felodipine Related Compound C;Felodipine Related Compound C diethyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate;Felodipine impurity C (EP);Felodipine EP Impurity C Nemadipine B;Felodipine Impurity 3(Felodipine EP Impurity C);4-(2,3-Dichlorophenyl)-1,4-dihydro-2,6-diMethyl-3,5-pyridinedicarboxylic Acid 3,5-Diethyl Ester;Felodipine EP IMpurity C
CAS:79925-38-5
MF:C19H21Cl2NO4
MW:398.28
EINECS:936-015-2
Product Categories:Aromatics;Dihydropyridine;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals
Mol File:79925-38-5.mol
NeMadipine B Structure
NeMadipine B Chemical Properties
Melting point 122-124°C
Boiling point 483.3±45.0 °C(Predicted)
density 1?+-.0.06 g/cm3(Predicted)
storage temp. Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
pka2.80±0.70(Predicted)
form Solid
color White to Pale Green
Safety Information
MSDS Information
NeMadipine B Usage And Synthesis
UsesA Diethyl ester analogue analogue of the calcium channel blocker Felodipine (F232375) with antihypertensive activity.
UsesNemadipine B (Felodipine EP Impurity C) is the diethyl ester analogue analogue of the calcium channel blocker Felodipine (F232375) with antihypertensive activity.
NeMadipine B Preparation Products And Raw materials
Raw materialsEthyl acetoacetate-->2,3-Dichlorobenzaldehyde
Preparation ProductsFelodipine
Felodipine Metabolite Lactone Felodipine Metabolite Lactone 4-(2,3-DICHLORO-PHENYL)-2,6-DIMETHYL-1,4-DIHYDRO-PYRIDINE-3,5-DICARBOXYLIC ACID MONOMETHYL ESTER Felodipine 3,5-DiMethyl Ester 4-(2,3-Dichlorophenyl)-2,6-diMethyl-1,4-dihydropyridine-3,5-dicarboxylic acid VEACAIASCBTOFS-LIJFRPJRSA-N Felodipine Felodipine Metabolite (5-carboxy-6-hydroxymethyl-dehydro Felodipine) DEHYDRO FELODIPINE-13C4

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