Triapine

Triapine Basic information

Product Name:	Triapine
Synonyms:	2-[(3-Amino-2-pyridinyl)methylene]hydrazinecarbothioamide;Hydrazinecarbothioamide, 2-[(3-amino-2-pyridinyl)methylene]-, (2E)-;Triapine USP/EP/BP;(E)-3-AP
CAS:	200933-27-3
MF:	C7H9N5S
MW:	195.24
EINECS:
Product Categories:	Inhibitors
Mol File:	200933-27-3.mol

Triapine Chemical Properties

Boiling point	436.0±55.0 °C(Predicted)
density	1.46
solubility	DMSO (Slightly), Methanol (Slightly)
form	Solid
pka	10.93±0.70(Predicted)
color	Pale Yellow to Dark Beige

Safety Information

MSDS Information

Triapine Usage And Synthesis

Uses

Triapine is a potent ribonucleotide reductase inhibitor with broad spectrum anti-tumor activity.

Biological Activity

Triapine (3-AP) is a potent ribonucleotide reductase (RNR) inhibitor with broad-spectrum antitumor activity by inhibiting DNA synthesis.

target

Target	Value
Ribonucleotide reductase

Triapine Preparation Products And Raw materials

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