ChemicalBook Product Catalog Pharmaceutical intermediates Heterocyclic compound Pyrimidines Chloropyrimidine 6-Chloro-1H-pyrazolo[3,4-d]pyrimidine

6-Chloro-1H-pyrazolo[3,4-d]pyrimidine

6-Chloro-1H-pyrazolo[3,4-d]pyrimidine Basic information
Product Name:6-Chloro-1H-pyrazolo[3,4-d]pyrimidine
Synonyms:6-Chloro-1H-pyrazolo[3,4-d]pyrimidine;1H-Pyrazolo[3,4-d]pyriMidine, 6-chloro-;2-Chlor-purin;6-Chlor-1H-pyrazolo<3,4-d>pyrimidin;QC-1184;6-chloro-1(2)H-pyrazolo[3,4-d]pyrimidine;6-Chloropyrazolo[3,4-d]pyrimidine
CAS:23002-51-9
MF:C5H3ClN4
MW:154.56
EINECS:
Product Categories:Heterocycle-Pyrimidine series;SF180085
Mol File:23002-51-9.mol
6-Chloro-1H-pyrazolo[3,4-d]pyrimidine Structure
6-Chloro-1H-pyrazolo[3,4-d]pyrimidine Chemical Properties
Melting point >100°C (dec.)
Boiling point 287.9±23.0 °C(Predicted)
density 1.84±0.1 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
solubility DMSO (Slightly), Ethyl Acetate (Slightly)
pka9.27±0.20(Predicted)
form Solid
color Pale Yellow
Stability:Moisture Sensitive
Safety Information
HS Code 2933998090
MSDS Information
6-Chloro-1H-pyrazolo[3,4-d]pyrimidine Usage And Synthesis
UsesPyrazolo[3,4-d]pyrimidines have a close structural resemblance to the substrates for the enzyme xanthine oxidase, hypoxanthine (6-hydroxypurine) and xanthine (2,6-dihydroxypurine). These compounds ar e capable of binding to the enzyme and strongly inhibit its activity. They have been studied for their role in the treatment and prophylaxis of hyperuricemia in human patients as well as potential an ti-tumor agents.
UsesPyrazolo[3,4-d]pyrimidines have a close structural resemblance to the substrates for the enzyme xanthine oxidase, hypoxanthine (6-hydroxypurine) and xanthine (2,6-dihydroxypurine). These compounds are capable of binding to the enzyme and strongly inhibit its activity. They have been studied for their role in the treatment and prophylaxis of hyperuricemia in human patients as well as potential anti-tumor agents.
6-Chloro-1H-pyrazolo[3,4-d]pyrimidine Preparation Products And Raw materials
1H-Indole-3-aceticacid,6-chloro-(9CI) 6-chloro-1H-pyrrolo[2,3-b]pyridin-2(3H)-one 6-chloro-1H-pyrrolo[3,2-c]pyridine-3-carbaldehyde 1H-1,2,3-TRIAZOLO[4,5-B]PYRIDINE, 6-CHLORO- 6-CHLORO-1H-PYRROLO[3,2-B]PYRIDINE 6-Chloro-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid methyl ester 1H-Pyrrolo[2,3-b]pyridine-3-carboxaldehyde, 6-chloro- 6-chloro-1H-pyrazolo[3,4-b]pyridine 6-CHLORO-1H-INDOL-3-METHYLAMINE
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