α,α-Dibromo-o-tolunitrile

α,α-Dibromo-o-tolunitrile Basic information
Product Name:α,α-Dibromo-o-tolunitrile
Synonyms:2-(Dibromomethyl)benzonitrile;o-Cyanobenzal bromide;o-Cyanobezylidene bromide;α,α-Dibromo-o-tolunitrile;Alogliptin Impurity O;Benzonitrile, 2-(dibromomethyl)-;Alogliptin Impurity 70;α,α-Dibromo-o-tolunitrile
CAS:655-63-0
MF:C8H5Br2N
MW:274.94
EINECS:
Product Categories:
Mol File:655-63-0.mol
α,α-Dibromo-o-tolunitrile Structure
α,α-Dibromo-o-tolunitrile Chemical Properties
Melting point 63-65°C
storage temp. Hygroscopic, Refrigerator, under inert atmosphere
solubility Chloroform (Slightly), Methanol (Slightly)
form Solid
color White to Off-White
Stability:Hygroscopic
Safety Information
MSDS Information
α,α-Dibromo-o-tolunitrile Usage And Synthesis
Uses2-Dibromomethyl-benzonitrile is an impurity of Alogliptin (A575425), which is an oral antihyperglycemic agent that is a selective inhibitor of the enzyme dipeptidyl peptidase-4 (DPP-4).Antidiabetic agent.
α,α-Dibromo-o-tolunitrile Preparation Products And Raw materials
2-[(6-CHLORO-2,4-DIOXO-3,4-DIHYDROPYRIMIDIN-1(2H)-YL)METHYL]BENZONITRILE o-Tolunitrile N-BOC-3-Aminopiperidine Alogliptin Related Compound 24 Alogliptin Related Compound 31 Alogliptin Impurity 10 Alogliptin Impurity 16 (R)-2-((6-(3-((3-(2-cyanobenzyl)-1-Methyl-2,6-dioxo-1,2,3,6-tetrahydropyriMidin-4-yl)aMino)piperidin-1-yl)-3-Methyl-2,4-dioxo-3,4-dihydropyriMidin-1(2H)-yl)Methyl)benzonitrile Alogliptin Impurity B Alogliptin Related Compound 21 Alogliptin Impurity 35 Alogliptin Related Compound 32 Alogliptin Impurity 34 Alogliptin Related Compound 18 (R)-2-((3-methyl-2,4-dioxo-6-(piperidin-3-ylamino)-3,4-Dihydro- pyrimidin-1(2H)-yl)methyl)benzonitrile hydrogen chloride Alogliptin Impurity 7 Alogliptin Impurity 29 Alogliptin Impurity 13 (S-Alogliptin Benzoate Salt)

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