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| | 1,3,5-Triazine Basic information |
| | 1,3,5-Triazine Chemical Properties |
| Melting point | 77-83 °C (dec.)(lit.) | | Boiling point | 114°C | | density | 1,38 g/cm3 | | refractive index | 1.5060 (estimate) | | Fp | 114°C | | storage temp. | Inert atmosphere,Room Temperature | | solubility | methanol: 0.1 g/mL, clear | | form | powder to crystal | | pka | 2.07±0.10(Predicted) | | color | White to Orange to Green | | Sensitive | Moisture Sensitive | | Merck | 14,9602 | | BRN | 104790 | | CAS DataBase Reference | 290-87-9(CAS DataBase Reference) | | NIST Chemistry Reference | 1,3,5-Triazine(290-87-9) |
| | 1,3,5-Triazine Usage And Synthesis |
| Chemical Properties | White crystal | | Application | 1,3,5-Triazine is a useful replacement for HCN in the Gattermann reaction for the synthesis of aromatic aldehydes. It reacts with nucleophiles, e.g. amines, which is utilized in quinazoline synthesis. | | Uses | 1,3,5-Triazine is a reagent in oxidation reactions, in synthesis of heterocycles. Triazine derivatives are used as herbicides, pharmaceuticals, complexation agents, peptidomimetic building blocks, and dyes.
| | Preparation | Symmetrical 1,3,5-triazines are prepared by trimerization of certain nitriles such as cyanogen chloride or cyanimide. Benzoguanamine (with one phenyl and 2 amino substituents) is synthesised from benzonitrile and dicyandiamide. In the Pinner triazine synthesis (named after Adolf Pinner) the reactants are an alkyl or aryl amidine and phosgene. Insertion of an N-H moiety into a hydrazide by a copper carbenoid, followed by treatment with ammonium chloride also gives the triazine core.
Amine-substituted triazines called Guanamines are prepared by the condensation of cyanoguanidine with the corresponding nitrile:
(H2N)2C=NCN + RCN → (CNH2)2(CR)N3 | | Definition | 1,3,5-Triazine, also known as s-triazine, is a six-membered ring organic compound, which is one of the isomers of triazine. |
| | 1,3,5-Triazine Preparation Products And Raw materials |
| Raw materials | 6-chloro-N2-phenyl-1,3,5-triazine-2,4-diamine-->2-Amino-1,3,5-triazine-->Methylamine nitrate-->Benzyl formimidate-hydrochloride-->Ethyl phenyl sulfone-->N-Methylformamide | | Preparation Products | METSULFURON METHYL-->Tribenuron methyl-->2-Amino-4-methoxy-6-methyl-1,3,5-triazine-->Cinosulfuron-->4-AMINOPYRIMIDINE-5-CARBOXAMIDE-->Terbutryn-->FORMAMIDINE HYDROCHLORIDE-->9H-Pyrimido[4,5-b]indole-->1-METHYL-1,2,4-TRIAZOLE-->2,4-Dichloro-1,3,5-triazine-->1,4,6-Triazaindene |
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