ChemicalBook Product Catalog Chemical Reagents Organic reagents Aromatic ketones 2-Chloro-4'-fluoroacetophenone

2-Chloro-4'-fluoroacetophenone

2-Chloro-4'-fluoroacetophenone Basic information
Product Name:2-Chloro-4'-fluoroacetophenone
Synonyms:2-Chloro-4'-fluoroacetophenone, 2-Chloro-1-(4-fluorophenyl)ethan-1-one;2-Bhloro-4'-fluoroacetophenone;Acetophenone, 2-chloro-4'-fluoro-;Acetophenone,2-chloro-4’-fluoro-;alpha-Chloro-p-fluoroacetophenone;Ethanone, 2-chloro-1-(4-fluorophenyl)-;Ethanone,2-chloro-1-(4-fluorophenyl)-(9CI);p-Fluorophenacyl chloride
CAS:456-04-2
MF:C8H6ClFO
MW:172.58
EINECS:207-256-4
Product Categories:Acetophenone series;(intermediate of fluvastatin);ACETYLHALIDE;456-04-2
Mol File:456-04-2.mol
2-Chloro-4'-fluoroacetophenone Structure
2-Chloro-4'-fluoroacetophenone Chemical Properties
Melting point 47-50 °C(lit.)
Boiling point 247°C
density 1.2752 (estimate)
vapor pressure 1.9Pa at 27.1℃
Fp >230 °F
storage temp. Inert atmosphere,Room Temperature
form Flakes or Platelets
color Light yellow to yellow-beige
Water Solubility Insoluble in water.
Sensitive Lachrymatory
BRN 637860
CAS DataBase Reference456-04-2(CAS DataBase Reference)
NIST Chemistry Reference«ALPHA»-chloro-para-fluoroacetophenone(456-04-2)
Safety Information
Hazard Codes Xi,C,T
Risk Statements 36/37/38-34-23/25-36
Safety Statements 26-28-45-36/37/39-27
RIDADR UN 3261 8/PG 2
WGK Germany 3
RTECS AM6550000
F 9-19
Hazard Note Corrosive/Lachrymatory
HazardClass 8
PackingGroup II
HS Code 29147000
MSDS Information
ProviderLanguage
4-Fluorophenacyl chloride English
SigmaAldrich English
ACROS English
ALFA English
2-Chloro-4'-fluoroacetophenone Usage And Synthesis
Chemical PropertiesLIGHT YELLOW TO YELLOW-BEIGE FLAKES OR PLATELETS
Uses1-methyl-2-(4-methylthio)phenyl-4-(4-fluoro)phenylimidazole which was synthesized by condensing N-methyl-4-(methylthio)benzamidine with 2-chloro-4?-fluoroacetophenone.
General Description2-Chloro-4′-fluoroacetophenone on condensation with N-methyl-4-(methylthio)benzamidine yields 1-methyl-2-(4-methylthio)phenyl-4-(4-fluoro)phenylimidazole.
2-Chloro-4'-fluoroacetophenone Preparation Products And Raw materials
Preparation Products1,2-BIS-(4-FLUOROPHENYL)ETHANONE-->3-(4-FLUORO-PHENYL)-1-ISOPROPYL-1H-INDOLE-2-CARBALDEHYDE-->Thiazole, 4-(4-fluorophenyl)-2-phenyl--->F90110-->5-(4-Fluoro-phenyl)-1H-pyrrole-3-carboxylic acid
N-(4'-fluorobutyrophenone)-4-(4-chlorophenyl)pyridinium 7-CHLORO-1-(4-FLUORO-PHENYL)-HEPTAN-1-ONE HALOPERIDOL RELATED COMPOUND A (15 MG) (4,4'-BIS[(4-P-CHLOROPHENYL)-4-HYDROXY-PIPERIDINO]-BU-TYROPHENONE) 4-[4-(4-Chlorophenyl)-4-hydroxy-1-piperidinyl]-1-(3-ethyl-4-fluorophenyl)-1-butanone Haloperidol EP Impurity E 3-CHLORO-7-FLUORO-3-PHENYL-1,2,3,4-TETRAHYDROQUINOLINE-2,4-DIONE 2'-Chloro-5'-fluoroacetophenone 97%,2'-Chloro-5'-fluoroacetophenone97%,2'-CHLORO-5'-FLUOROACETOPHENONE,2-CHLORO-5-FLUOROACETOPHENONE 4'-CHLORO-2'-FLUOROACETOPHENONE,4-CHLORO-2-FLUOROACETOPHENONE 3-Chloro-1-(4-fluorophenyl)propan-1-one 2-Chloro-2',4'-difluoroacetophenone Trifluoroacetophenone ACETYL FLUORIDE 2-BROMO-3'-CHLORO-4'-FLUOROACETOPHENONE 5'-CHLORO-2'-FLUOROACETOPHENONE L-PICEIN 2-Bromoacetophenone 1-(2,6-Difluorophenyl)ethan-1-one 2-​[[(2-​ethylphenyl)​(2-​hydroxyethyl)​amino]​methyl]​-​3,​3-​difluoro-Propanenitrile
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