PROPARGYLAMINE

PROPARGYLAMINE Basic information
Product Name:PROPARGYLAMINE
Synonyms:Propargulamine;AURORA KA-2552;2-propyn-1-amine;2-PROPYNYLAMINE;3-AMINO-1-PROPIN;3-AMINO-1-PROPYNE;Prop-2-ynylamine, tech. (mono-Propargylamine);POTASSIUM TER-BUTOXIDE
CAS:2450-71-7
MF:C3H5N
MW:55.08
EINECS:219-513-8
Product Categories:Acetylenes;Functionalized Acetylenes;Amines;blocks;Amines and Anilines
Mol File:2450-71-7.mol
PROPARGYLAMINE Structure
PROPARGYLAMINE Chemical Properties
Boiling point 84 °C
density 0.86
refractive index n20/D 1.449(lit.)
Fp 39 °F
storage temp. 2-8°C
solubility soluble in Chloroform, Ethyl Acetate
pka7.89±0.29(Predicted)
form Liquid
color Clear colorless to yellow
Water Solubility miscible
Sensitive Air Sensitive
BRN 773681
CAS DataBase Reference2450-71-7(CAS DataBase Reference)
NIST Chemistry ReferencePropargylamine(2450-71-7)
EPA Substance Registry System2-Propyn-1-amine (2450-71-7)
Safety Information
Hazard Codes F,T
Risk Statements 11-22-24-34
Safety Statements 16-26-33-36/37/39-45-28A
RIDADR UN 1992 3/PG 2
WGK Germany 3
RTECS UK5250000
3-8-10-34
TSCA Yes
HazardClass 3.1
PackingGroup II
HS Code 29211990
MSDS Information
ProviderLanguage
2-Propyn-1-amine English
SigmaAldrich English
ACROS English
PROPARGYLAMINE Usage And Synthesis
Chemical Propertiesclear colorless to yellow liquid
UsesA useful intermediates in the preparation of drugs or pesticides.
UsesPropargylamine is used in the synthesis of a chiral, a fluorescent macrocycle by 1,3-dipolar cycloaddition of propargyl amides of carbohydrate-linked amino acids and 9,10-bis(azidomethyl)anthracene. It acts as an intermediate in the production of drugs.
UsesSynthesis of a chiral, fluorescent macrocycle by 1,3-dipolar cycloaddition of propargyl amides of carbohydrate-linked amino acids and 9,10-bis(azidomethyl)anthracene.
Enzyme inhibitorThis alkynyl amine HCCCH2–NH2 (FWfree-base = 55.08 g/mol), also known as propargylamine and 3-amino-1-propyne, is a toxic liquid that boils at 83°C. The water-soluble hydrochloride melts at 179-182°C. Target(s): aldehyde dehydrogenase; diamine oxidase, or amine oxidase [copper-containing]; glycine cleavage complex, or glycine synthase; and monoamine oxidase, or amine oxidase [flavin-containing].
PARGYLINE HYDROCHLORIDE rich-d-t-Prallethrin Diisopropylammonium dichloroacetate Propyne 3-Bromopropyne FLUMIOXAZIN (-)-2-[METHYLAMINO]-1-PHENYLPROPANE Triallylamine Propargyl alcohol D/L-AMPHETAMINE HYDROCHLORIDE Dibenzylamine :(S)-2-Methyl-3-(2-propynyl)-4-oxocyclopent-2-enyl-(lR)-cis,trans-2,2-dimethyl-3-(2-methyl-1-propenyl)cyclopropanecarboxylate Bis(2-ethylhexyl)amine Propyzamide Propiolic Acid Isopropylamine PROPARGYLAMINE Triethanolamine

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