3-Hydroxy-4-methoxycinnamic acid

3-Hydroxy-4-methoxycinnamic acid Basic information
Product Name:3-Hydroxy-4-methoxycinnamic acid
Synonyms:ISOFERULIC ACID;HESPERETINIC ACID;HESPERETIC ACID;3-HYDROXY-4-METHOXYCINNAMIC ACID;AKOS BBS-00006960;(2E)-3-(3-HYDROXY-4-METHOXYPHENYL)ACRYLIC ACID;(2E)-3-(3-Hydroxy-4-methoxyphenyl)-2-propenoic acid;2-Propenoic acid, 3-(3-hydroxy-4-methoxyphenyl)-
CAS:537-73-5
MF:C10H10O4
MW:194.18
EINECS:208-676-0
Product Categories:Inhibitors;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;Pharmaceutical Raw Materials;Aromatic Cinnamic Acids, Esters and Derivatives;Cinnamic acid;Aromatics Compounds;Aromatics;C10;Carbonyl Compounds;Carboxylic Acids
Mol File:537-73-5.mol
3-Hydroxy-4-methoxycinnamic acid Structure
3-Hydroxy-4-methoxycinnamic acid Chemical Properties
Melting point 230 °C (dec.)(lit.)
Boiling point 250.62°C (rough estimate)
density 1.0583 (rough estimate)
refractive index 1.5168 (estimate)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility Soluble in ethanol and methanol.
form Solid
pka4.53±0.10(Predicted)
color Pale Yellow
BRN 2212760
LogP0.788 (est)
CAS DataBase Reference537-73-5(CAS DataBase Reference)
NIST Chemistry ReferenceCinnamic acid, 3-hydroxy-4-methoxy-(537-73-5)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-37/39-24/25
WGK Germany 2
RTECS UD3365400
Hazard Note Irritant
HS Code 29189090
MSDS Information
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3-Hydroxy-4-methoxycinnamic acid English
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3-Hydroxy-4-methoxycinnamic acid Usage And Synthesis
Chemical PropertiesOff-White Crystalline Solid
Uses3-Hydroxy-4-methoxycinnamic Acid (Isoferulic acid) is a hypoglycemic agent.
Uses3-Hydroxy-4-methoxycinnamic acid exhibits hypoglycemic properties.
Uses3-Hydroxy-4-methoxycinnamic acid was used in the synthesis of tranilast and various tranilast analogs (cinnamoyl anthranilates) by genetically engineered Saccharomyces cerevisiae yeast strain. It was also used in the synthesis of glycoside compounds by undergoing glycosidation.
DefinitionChEBI: A ferulic acid consisting of trans-cinnamic acid bearing methoxy and hydroxy substituents at positions 4 and 3 respectively on the phenyl ring.
General Description3-Hydroxy-4-methoxycinnamic acid, predominantly trans is available as white crystals. 3-Hydroxy-4-methoxycinnamic acid is isolated from the aerial part of Artemisia capillaris, Chinese medicinal plant. It is a component of chinese herbal medicine used for a pain killer and stomachic. It is an efficient acetylcholine inhibitor. 3-Hydroxy-4-methoxycinnamic acid is bioactive metabolite of Spilanthes acmella Murr. It increases the resistance of low-density lipoprotein (LDL) to oxidation.
3-Hydroxy-4-methoxycinnamic acid Preparation Products And Raw materials
3-Hydroxycinnamic acid alpha-Methylcinnamic acid 2-BROMO-4,5-METHYLENEDIOXYCINNAMIC ACID 3,4,5-TRIMETHOXYCINNAMIC ACID ETHYL ESTER 3,4-Dimethoxycinnamonitrile 2-PHENYL-4-PIPERONYLIDENE-2-OXAZOLIN-5-ONE N-BUTYL CINNAMATE Methyl cinnamate 4,5-DIMETHOXY-2-NITROCINNAMIC ACID trans-Cinnamic acid 2,3-DIHYDROXY-4-METHOXYCINNAMIC ACID HYDROXYCINNAMIC ACID 4-Methoxycinnamic acid trans-2,3,4-Trimethoxycinnamic acid 4-Hydroxycinnamic acid 3-Hydroxy-4-methoxycinnamic acid CHLOROPHOSPHONAZO III Ethyl cinnamate

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