6-Hydroxy-2(1H)-3,4-dihydroquinolinone

6-Hydroxy-2(1H)-3,4-dihydroquinolinone Basic information

Product Name:	6-Hydroxy-2(1H)-3,4-dihydroquinolinone
Synonyms:	6-HYDROXY-3,4-DIHYDRO-1H-QUINOLIN-2-ONE;TQ(3,4-Dihydro-6-Hydroxy-2(1H)CQuinolinone);TQ(3,4-DIHYDRO-6-HYDROXY-2(1H)QUINOLINONE);Hydroxyl-3,4-dihydrocarbostyril;6-Hydroxy-1,2,3,4-tetrahydro-2-quinolinone, 6-Hydroxy-3,4-dihydrocarbstyril;3,4-Dihydro-2,6-quinolinediol;3,4-Dihydro-6-hydroxyquinoline-2(1H)-one;6-Hydroxy-3,4-dihydroquinoline-2(1H)-one
CAS:	54197-66-9
MF:	C9H9NO2
MW:	163.17
EINECS:	611-111-4
Product Categories:	Fluorobenzene;Alcohols and Derivatives;Heterocycles;Aromatic Ethers;Quinoline derivatives;API intermediates;(intermediate of cilostazol);Various Metabolites and Impurities;Intermediates & Fine Chemicals;Metabolites & Impurities;Pharmaceuticals
Mol File:	54197-66-9.mol

6-Hydroxy-2(1H)-3,4-dihydroquinolinone Chemical Properties

Melting point	236-240 °C
Boiling point	424.5±45.0 °C(Predicted)
density	1.282±0.06 g/cm3(Predicted)
storage temp.	Sealed in dry,Room Temperature
solubility	DMSO (Slightly), Methanol (Slightly, Heated)
pka	9.86±0.20(Predicted)
form	neat
color	White to Almost white
CAS DataBase Reference	54197-66-9(CAS DataBase Reference)

Safety Information

MSDS Information

6-Hydroxy-2(1H)-3,4-dihydroquinolinone Usage And Synthesis

Chemical Properties	Off-white solid
Uses	A metabolite of Cilostazole.

6-Hydroxy-2(1H)-3,4-dihydroquinolinone Preparation Products And Raw materials

Raw materials	2-Propenoic acid, 3-(5-hydroxy-2-nitrophenyl)--->3-CHLORO-N-(4-METHOXYPHENYL)PROPANAMIDE-->3-CHLORO-N-PHENYLPROPANAMIDE-->1,2,3,4-Tetrahydroquinoline-->6-AMINO-3,4-DIHYDRO-1H-QUINOLIN-2-ONE-->3-CHLORO-N-(4-ETHOXYPHENYL)PROPANAMIDE-->3-CHLORO-N-(4-HYDROXYPHENYL)PROPIONAMIDE-->3,4-DIHYDROQUINOLIN-2(1H)-ONE-->Aluminum chloride-->p-Anisidine
Preparation Products	Disperse Yellow HG-->Nedocromil-->Cilostazol Related Compound C (50 mg) (1-(4-(5-Cyclohexyl-1H-tetrazol-1-yl)butyl)-6-(4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy)-3,4-dihydroquinolin-2(1H)-one)

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