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TERT-BUTYL (R)-6-CHLORO-5-HYDROXY-3-OXOHEXANOATE

TERT-BUTYL (R)-6-CHLORO-5-HYDROXY-3-OXOHEXANOATE Basic information
Product Name:TERT-BUTYL (R)-6-CHLORO-5-HYDROXY-3-OXOHEXANOATE
Synonyms:TERT-BUTYL (R)-6-CHLORO-5-HYDROXY-3-OXOHEXANOATE;(R)-tert-butyl 6-chloro-5-hydroxy-3-oxohexanoate;tert-Butyl 6-Chloro-(R)-hydroxy-3-oxohexanoate;Rosuvastatin Impurity 112;Hexanoic acid, 6-chloro-5-hydroxy-3-oxo-, 1,1-dimethylethyl ester, (5R)-;(R)-tert-butyl 6-chloro-5-hydroxy-3-oxohexanoate? (Rosuvastatin Impurity）
CAS:404958-08-3
MF:C10H17ClO4
MW:236.69
EINECS:
Product Categories:
Mol File:404958-08-3.mol
TERT-BUTYL (R)-6-CHLORO-5-HYDROXY-3-OXOHEXANOATE Structure
TERT-BUTYL (R)-6-CHLORO-5-HYDROXY-3-OXOHEXANOATE Chemical Properties
Boiling point 331.1±32.0 °C(Predicted)
density 1.162±0.06 g/cm3(Predicted)
pka10.33±0.46(Predicted)
Safety Information
MSDS Information
TERT-BUTYL (R)-6-CHLORO-5-HYDROXY-3-OXOHEXANOATE Usage And Synthesis
Usestert-Butyl 6-Chloro(R)-hydroxy-3-oxohexanoate is a chiral reagent used in the synthesis of callystatin A, a polyketide natural product that functions as an antibiotic. Also an impurity in the synthesis of Rosuvastatin (R700500), a selective, competitive HMG-CoA reductase inhibitor. Antilipemic.
TERT-BUTYL (R)-6-CHLORO-5-HYDROXY-3-OXOHEXANOATE Preparation Products And Raw materials
Rosuvastatin Impurity 4 Phosphonium, [[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]me 5-PyriMidinecarboxylic acid, 4-(4-fluorophenyl)-1,2-dihydro-6-(1-Methylethyl)-2-oxo-, Methyl ester Desfluoro Rosuvastatin Sodium Salt Rosuvastatin EP impurity H Rosuvastatin EP Impurity C 4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidine-5-carboxylic acid NGABCYSYENPREI-RYUDHWBXSA-N tert-Butyl 2-((4S,6S)-6-(chloromethyl(02,2-1,3-dioxan-4-yl)acetate Rosuvastatin Calcium Salt Rosuvastatin Related Compound 8 Rosuvastatin Impurity 91 (4R-Cis)-6-Hydroxymethyl-2,2-dimethyl-1,3-dioxane-4-acetic acid 1,1-dimethylethyl ester tert-butyl (3R,5S)-6-chloro-3,5-dihydroxyhexanoate N-Desmethyl Rosuvastatin Lactone 3-Oxo Rosuvastatin SodiuM Salt N-[(6R)-8-Fluoro-5,6-dihydro-4-(1-Methylethyl)-6-[(2S,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]benzo[h]quinazolin-2-yl]-N-MethylMethanesulfonaMide 4-(4-Fluorophenyl)-6-isopropyl-2-[(N-methyl-N-methylsulfonyl)amino]pyrimidinyl-5-yl-formyl
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