Bitolterol

Bitolterol Basic information
Product Name:Bitolterol
Synonyms:Bis(4-methylbenzoic acid)4-[2-(tert-butylamino)-1-hydroxyethyl]-1,2-phenylene ester;Bis(p-toluic acid)4-[2-(tert-butylamino)-1-hydroxyethyl]-1,2-phenylene ester;C06853;Benzoic acid, 4-methyl-, 1,1'-[4-[2-[(1,1-dimethylethyl)amino]-1-hydroxyethyl]-1,2-phenylene] ester;Bitolterol USP/EP/BP
CAS:30392-40-6
MF:C28H31NO5
MW:461.55
EINECS:
Product Categories:Aromatics, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals
Mol File:30392-40-6.mol
Bitolterol Structure
Bitolterol Chemical Properties
Boiling point 640.5±55.0 °C(Predicted)
density 1.169±0.06 g/cm3(Predicted)
pka13.61±0.20(Predicted)
Safety Information
MSDS Information
Bitolterol Usage And Synthesis
UsesBitolterol is a is a β2-adrenergic receptor agonist used for the relief of bronchospasm in conditions such as asthma and COPD.
DefinitionChEBI: Bitolterol is the di-4-toluate ester of (+-)-N-tert-butylnoradrenaline (colterol). A pro-drug for colterol, a beta2-adrenergic receptor agonist, bitolterol is used as its methanesulfonate salt for relief of bronchospasm in conditions such as asthma, chronic bronchitis and emphysema. It has a role as a bronchodilator agent, an anti-asthmatic drug, a beta-adrenergic agonist and a prodrug. It is a member of ethanolamines, a carboxylic ester, a diester, a secondary amino compound and a secondary alcohol.
Brand nameTornalate (Sanofi Aventis).
Bitolterol Preparation Products And Raw materials
3-BENZYLOXY-4-METHOXYBENZYL ALCOHOL RARECHEM AN KA 0136 2-amino-1-(4-ethoxyphenyl)ethanol 1,2-DIACETOXYBENZENE Metiprenaline 3-METHOXY-4-ACETOXY BENZYL ALCOHOL 3-PHENOXYPHENETHYLAMINE Colterol CHEMBRDG-BB 5535468 normacromerine 1-(3-ETHOXY-PHENYL)-2-METHYLAMINO-ETHANOL 3,4-Diethoxybenzyl alcohol Levisoprenaline ALPHA-METHYL-(3-BENZYLOXY)BENZYL ALCOHOL 4-BENZYLOXY-3-METHOXYBENZYL ALCOHOL Bitolterol 2-AMINO-1-(3,4-DIMETHOXY-PHENYL)-ETHANOL (tert-butyl)[beta-hydroxy-3,4-bis(p-toluoyloxy)phenethyl]ammonium methanesulphonate

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