| | 2-Bromotoluene Basic information |
| | 2-Bromotoluene Chemical Properties |
| Melting point | -27 °C (lit.) | | Boiling point | 58-60 °C/10 mmHg (lit.) | | density | 1.422 g/mL at 25 °C (lit.) | | refractive index | n20/D 1.555(lit.) | | Fp | 174 °F | | storage temp. | 2-8°C | | form | Liquid | | color | Clear colorless to light yellow | | Specific Gravity | 1.422 | | Water Solubility | <0.1 g/100 mL at 15 ºC | | Merck | 14,1439 | | BRN | 1904176 | | Stability: | Stable. Incompatible with strong oxidizing agents. | | CAS DataBase Reference | 95-46-5(CAS DataBase Reference) | | NIST Chemistry Reference | Benzene, 1-bromo-2-methyl-(95-46-5) | | EPA Substance Registry System | o-Bromotoluene (95-46-5) |
| | 2-Bromotoluene Usage And Synthesis |
| Chemical Properties | liquid | | Uses | 2-Bromotoluene was used in the synthesis of (±)-isocomene. Suzuki coupling of 2-bromotoluene with phenylboronic acid using palladium nanoparticles supported on alumina-based oxides as catalyst has been reported. 2-Bromotoluene is used in manufacturing pharmaceuticals (especially for nonsteroidal antiinflammatory drugs; Meclofenamic acid, Mefenamic acid) and other organic compounds | | General Description | Clear colorless to pale beige liquid. | | Air & Water Reactions | Insoluble in water. | | Reactivity Profile | 2-Bromotoluene reacts with strong oxidizing agents. | | Fire Hazard | 2-Bromotoluene is combustible. | | Purification Methods | Fractionally distil it through an efficient column. It can be separated from its isomers by gas chromatography on a column of “Sil-o-cel” firebrick (30-40mesh, 80 parts) coated with 5% (20 parts) of ICI E301 con rubber with N2 carrier gas at 170o/atm and 100mL/minute and using a conductivity cell detector. [Cowley et al. J Chem Soc 1801 1959, Beilstein 5 H 304, 5 I 153, 5 II 234 5 III 704, 5 IV 825.] |
| | 2-Bromotoluene Preparation Products And Raw materials |
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