2,5-Dichlorophenol

2,5-Dichlorophenol Basic information
Product Name:2,5-Dichlorophenol
Synonyms:2,5-dichloro-pheno;6-HYDROXY-1,4-DICHLOROBENZENE;2,5-DICHLORO-1-HYDROXY-BENZENE;2,5-DICHLOROPHENOL;2,5-DCP;DICHLOROPHENOL-2,5;Dichlorophenol,98%;2,5-DICHLOROPHENOL PESTANAL
CAS:583-78-8
MF:C6H4Cl2O
MW:163
EINECS:209-520-4
Product Categories:Aromatic Phenols;Organics;Phenol&Thiophenol&Mercaptan;Phenoles and thiophenoles;Chlorine Compounds;Phenols;Alpha sort;D;DAlphabetic;DIA - DIC;Pesticides&Metabolites;Organic Building Blocks;Oxygen Compounds;Volatiles/ Semivolatiles;K00001
Mol File:583-78-8.mol
2,5-Dichlorophenol Structure
2,5-Dichlorophenol Chemical Properties
Melting point 54-57 °C (lit.)
Boiling point 211 °C (lit.)
density 1.3446 (rough estimate)
refractive index 1.4430 (estimate)
Fp 100 °C
storage temp. 0-6°C
solubility 2000mg/l (experimental)
pka7.53±0.10(Predicted)
form Crystals
color White to light brown
Water Solubility 3 g/L (20 ºC)
BRN 1907692
LogP3.06 at 20℃
CAS DataBase Reference583-78-8(CAS DataBase Reference)
NIST Chemistry ReferencePhenol, 2,5-dichloro-(583-78-8)
EPA Substance Registry System2,5-Dichlorophenol (583-78-8)
Safety Information
Hazard Codes C,N,Xn
Risk Statements 22-34-51/53-36/38
Safety Statements 26-36/37/39-45-61-37/39
RIDADR UN 2020 6.1/PG 3
WGK Germany 2
RTECS SK8600000
TSCA Yes
HazardClass 6.1
PackingGroup III
HS Code 29081000
Hazardous Substances Data583-78-8(Hazardous Substances Data)
ToxicityLD50 orally in Rabbit: 580 mg/kg
MSDS Information
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2,5-Dichlorophenol Usage And Synthesis
Chemical Propertieswhite to light brown crystals
Uses2,5-Dichlorophenol is an intermediates in the manufacture of more complex chemical compounds such as fungicides.
Uses2,5-Dichlorophenol may be used as an analytical reference standard for the determination of the analyte in water, and wood, paper, cardboard, fruits, and fruit juices using simultaneous dispersive liquid-liquid microextraction and derivatization followed by gas chromatography-electron-capture detection (GC-ECD) and gas chromatography-mass spectrometry (GC-MS), respectively.
DefinitionChEBI: A dichlorophenol with the chloro substituents at positions 2 and 5.
Synthesis Reference(s)Journal of the American Chemical Society, 74, p. 3890, 1952 DOI: 10.1021/ja01135a052
General DescriptionPrisms (from benzene, petroleum ether) or white crystals. Odor threshold 30 μg/L at 68-72°F; 33 μg/L at 86°F. Taste threshold 0.5 μg/L.
Air & Water ReactionsInsoluble in water.
Reactivity Profile2,5-Dichlorophenol is incompatible with acid chlorides, acid anhydrides and oxidizing agents.
Fire HazardFlash point data for 2,5-Dichlorophenol are not available. 2,5-Dichlorophenol is probably combustible.
Purification MethodsCrystallise it from ligroin and sublime it in a vacuum or distil it. [Beilstein 6 IV 942.]
2-Phenylphenol 3,5-DICHLOROPHENOL TYPICALLY 99% TETRACHLOROCATECHOL Quinclorac 2,3,6-TRICHLOROPHENOL 2,4-DICHLOROPHENOL pract,2,4-DICHLOROPHENOL 99+% 2',4'-Dichloroacetophenone 2,4,5-Trichlorophenoxyacetic acid 2,6-DICHLOROPHENOL extrapure 1,2-Dichloroethane 2,3,5,6-TETRACHLOROANISOLE 2,3-DICHLOROPHENOL 99+% Hexachlorophene N,N-Dimethylacetamide 2,5-Dichlorophenol Dichloroethane Sodium dichloroisocyanurate Thionyl chloride

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