Diisopropanolamine

Diisopropanolamine Basic information
Product Name:Diisopropanolamine
Synonyms:2-Propanol, 1,1'-iminobis-;2-Propanol, 1,1'-iminodi-;Bis(2-propanol)amine;Di(2-hydroxy-n-propyl) amine;DI(2-Hydroxy-n-propyl)amine;DIPA commercial grade;DIPA low freeze grade 85;DIPA low freeze grade 90
CAS:110-97-4
MF:C6H15NO2
MW:133.19
EINECS:203-820-9
Product Categories:Amino Alcohols;Building Blocks;Cosmetic Ingredients & Chemicals;Chemical Synthesis;Organic Building Blocks;Oxygen Compounds
Mol File:110-97-4.mol
Diisopropanolamine Structure
Diisopropanolamine Chemical Properties
Melting point 42-45 °C(lit.)
Boiling point 249-250 °C745 mm Hg(lit.)
density 1.004 g/mL at 25 °C(lit.)
vapor pressure 0.02 hPa (20 °C)
refractive index 1.4615-1.4635
Fp 260 °F
storage temp. Store below +30°C.
solubility H2O: miscible
form Low Melting Solid
pka14.54±0.20(Predicted)
Specific Gravity0.99
color Colorless to light yellow
PH11.4 (100g/l, H2O, 20℃)
OdorFishy; ammoniacal.
explosive limit1.6-8.0%(V)
Water Solubility 870 G/L (20 ºC)
Sensitive Air Sensitive & Hygroscopic
Merck 14,3195
BRN 605363
Stability:Hygroscopic
LogP-0.79 at 20℃
CAS DataBase Reference110-97-4(CAS DataBase Reference)
NIST Chemistry ReferenceDiisopropanolamine(110-97-4)
EPA Substance Registry SystemDiisopropanolamine (110-97-4)
Safety Information
Hazard Codes Xi
Risk Statements 36
Safety Statements 26
RIDADR 3259
WGK Germany 1
RTECS UB6600000
3-34
Autoignition Temperature290 °C
TSCA Yes
HS Code 2922 19 00
HazardClass 8
PackingGroup III
Hazardous Substances Data110-97-4(Hazardous Substances Data)
ToxicityLD50 orally in Rabbit: 4765 mg/kg LD50 dermal Rabbit 8000 mg/kg
MSDS Information
ProviderLanguage
ACROS English
SigmaAldrich English
ALFA English
Diisopropanolamine Usage And Synthesis
Chemical Propertiesclear colorless liquid after melting
Chemical PropertiesDiisopropanolamine is a corrosive, hygroscopic solid (18, 139).
UsesBis(2-hydroxypropyl)amine (Diisopropanolamine) is used to study its effects upon choline uptake and phospholipid synthesis in Chinese hamster ovary (CHO) cells. It is a versatile chemical that is widely used as an emulsifier, stabilizer, surfactant, and chemical building block. It can neutralize pH, act as a buffer (stabilize pH), or add basicity (alkalinity) to a solution. Major applications include personal care products, metalworking products, and natural gas purification. Diisopropanolamine is also used in coatings, paint strippers, paper, photographic intermediates, plastics, polyurethanes, and textiles. It is frequently used to neutralize fatty acids and sulfonic acidbased surfactants.
UsesDiisopropanolamine was used to study its effects upon choline uptake and phospholipid synthesis in Chinese hamster ovary (CHO) cells
UsesEmulsifying and neutralizing agent in cosmetics. Removal of H2S and CO2 from natural and industrial gases. Antimicrobial agent in cutting fluids.
DefinitionChEBI: Diisopropanolamine is a secondary amino compound that is diethanolamine substituted by methyl groups at positions 1 and 1'. It is a versatile chemical used in a variety of personal care, cosmetic and industrial products. It has a role as a surfactant, an emulsifier and a buffer. It is a secondary amino compound, a secondary alcohol and an aminodiol. It is functionally related to a 1-aminopropan-2-ol.
General DescriptionColorless liquid or white to yellow crystalline solid with an odor of dead fish or ammonia. Liquid floats and mixes with water. Solid sinks and mixes in water.
Air & Water ReactionsWater soluble.
Reactivity ProfileDiisopropanolamine is an aminoalcohol. Amines are chemical bases. They neutralize acids to form salts plus water. These acid-base reactions are exothermic. The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides. Diisopropanolamine may be sensitive to light and air. Diisopropanolamine will react with oxidizing materials.
Health HazardVapor concentrations too low to irritate unless exposure is prolonged. Liquid will burn eyes and skin.
Fire HazardDiisopropanolamine is combustible.
Flammability and ExplosibilityNonflammable
Chemical ReactivityReactivity with Water No reaction; Reactivity with Common Materials: No reaction; Stability During Transport: Stable; Neutralizing Agents for Acids and Caustics: Flush with water; Polymerization: Not pertinent; Inhibitor of Polymerization: Not pertinent.
Purification MethodsCrystallise the amine repeatedly from dry diethyl ether. [Beilstein 4 III 761.]
Diisopropanolamine Preparation Products And Raw materials
Raw materialsAmino-2-propanol-->2,6-DICHLOROPHENOLINDOPHENYL ACETATE-->3-(2-HYDROXYPROPYL)-5-METHYL-2-OXAZOLIDINONE
Preparation ProductsSilk softener L-->1,1'-(dodecylimino)dipropan-2-ol
Hydroxypropyl cellulose Dipropylamine Amino-2-propanol 5-(TERT-BUTYL)-2-IODO-1,3-DIMETHYLBENZENE N-Ethylmethylamine D/L-AMPHETAMINE HYDROCHLORIDE 1-Hydroxyethylidene-1,1-diphosphonic acid Dibenzylamine Triethylamine 1-Dimethylamino-2-propanol Triclosan Bis(2-ethylhexyl)amine Allylamine Propylamine Isopropyl alcohol Isopropylamine Triethanolamine 1-Propanol

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