PAGOCLONE

PAGOCLONE Basic information
Product Name:PAGOCLONE
Synonyms:2-(7-Chloro-1,8-naphthyridin-2-yl)-3-(5-methyl-2-oxohexyl)-1-isoindolinone;RP 59037;Ip 456;Rp 62955;2-(7-Chloro-1,8-naphthyridin-2-yl)-3-(5-Methyl-2-oxohexyl)isoindolin-1-one;(+)-RP-59037; IP-456; RP-62955; CI-1043;CI-1043;AGOCLONE
CAS:133737-32-3
MF:C23H22ClN3O2
MW:407.89
EINECS:225-799-5
Product Categories:
Mol File:133737-32-3.mol
PAGOCLONE Structure
PAGOCLONE Chemical Properties
Boiling point 582.1±50.0 °C(Predicted)
density 1.273±0.06 g/cm3(Predicted)
pka1.62±0.30(Predicted)
Safety Information
MSDS Information
PAGOCLONE Usage And Synthesis
DescriptionPagoclone is a drug that belongs to the class of cyclopyrrolones. It binds to the benzodiazepine binding site on GABAA receptors and acts as a negative allosteric modulator, thereby enhancing the inhibitory effects of GABA and reducing neuronal excitability.
UsesAnti-anxiety agent.
ApplicationPagoclone has been shown to have anti-inflammatory properties in an animal model of inflammatory bowel disease and may be useful for the treatment of this condition.
Brand nameBextra (Interneuron).
PAGOCLONE Preparation Products And Raw materials
IMIPRAMINE Olanzapine Venlafaxine Risperidone 2-CHLORO-1,8-NAPHTHYRIDINE PAGOCLONE

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