Pagoclone is a drug that belongs to the class of cyclopyrrolones. It binds to the benzodiazepine binding site on GABAA receptors and acts as a negative allosteric modulator, thereby enhancing the inhibitory effects of GABA and reducing neuronal excitability.
Uses
Anti-anxiety agent.
Application
Pagoclone has been shown to have anti-inflammatory properties in an animal model of inflammatory bowel disease and may be useful for the treatment of this condition.