3-Hydroxypicolinic acid

3-Hydroxypicolinic acid Basic information

Product Name:	3-Hydroxypicolinic acid
Synonyms:	2-PYRIDINECARBOXYLIC ACID, 3-HYDROXY-;3-HYDROXYPYRIDINE-2-CARBOXYLIC ACID;3-HYDROXYPICOLINIC ACID;3-HPA;3-HYDROXY-2-PYRIDINECARBOXYLIC ACID;TIMTEC-BB SBB006727;RARECHEM AL BO 0972;3-Hydroxy-2-Pyridinecarboxylic
CAS:	874-24-8
MF:	C6H5NO3
MW:	139.11
EINECS:	212-859-0
Product Categories:	alcohol\| carboxylic acid;Pyridine;Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts;Pyridine series;Organic acids;Pyridines;Analytical Chemistry;Mass Spectrometry;Matrix Materials (MALDI-TOF-MS)
Mol File:	874-24-8.mol

3-Hydroxypicolinic acid Chemical Properties

Melting point	213-218 °C (lit.)
Boiling point	255.04°C (rough estimate)
density	1.4429 (rough estimate)
refractive index	1.5423 (estimate)
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
solubility	Acetonitrile (Slightly), DMSO (Slightly)
form	Fine Powder
pka	1.14±0.50(Predicted)
color	White to almost white
Water Solubility	Soluble in water (0.25g in 10ml).
BRN	118954
CAS DataBase Reference	874-24-8(CAS DataBase Reference)
NIST Chemistry Reference	3-Hydroxypicolinic acid(874-24-8)

Safety Information

Hazard Codes	Xi,Xn
Risk Statements	36/37/38-20/22
Safety Statements	26-28-36/37/39-36
WGK Germany	3
F	10
HazardClass	IRRITANT
HS Code	29333990

MSDS Information

Provider	Language
3-Hydroxy-2-pyridinecarboxylic acid	English
ACROS	English
SigmaAldrich	English
ALFA	English

3-Hydroxypicolinic acid Usage And Synthesis

Chemical Properties	Light yellow Needles
Uses	3-Hydroxypicolinic acid (3-HPA) is a matrix material used in matrix-assisted laser desorption/ionization (MALDI) based mass spectroscopy (MS) for the analysis of large biomolecules and quantification of oligonucleotides.
Definition	ChEBI: A monohydroxypyridine that is picolinic acid in which the hydrogen at position 3 is replaced by a hydroxy group. It is used as a matrix in matrix-assisted laser desorption/ionization (MALDI) mass spectrometry for the analysis of oligonucleotides.

3-Hydroxypicolinic acid Preparation Products And Raw materials

Raw materials	desferriferrithiocin-->D-Cysteine, 2-methyl- (9CI)-->3-hydroxypyrido[3,2-d][1,2,3]triazin-4(3H)-one-->2-Pyridinecarboxamide,3-amino-N-hydroxy-(9CI)-->3-Aminopyridine-2-carboxylic acid ethyl ester-->3-Pyridinol N-oxide-->2-CYANO-3-HYDROXYPYRIDINE-->3-Hydroxypyridine-2-carboxaldehyde-->3-Amino-2-pyridinecarboxylic acid-->3-Hydroxy-2-methylpyridine-->3-Hydroxypyridine
Preparation Products	3-METHOXY-2-PYRIDINECARBOXYLIC ACID-->3-HYDROXY-PYRIDINE-2-CARBOXYLIC ACID METHYL ESTER-->4-[(3-hydroxy-2-pyridyl)carbonyl]morpholine-->3-(Benzyloxy)-6-broMo-4-Methoxypicolinic acid

Methylparaben 4-Hydroxybenzoic acid Salicylic acid Ethyl 2-(Chlorosulfonyl)acetate 2'-Hydroxy-3-phenylpropiophenone Ascoric Acid 3-Hydroxybenzoic acid Folic acid Glycine Chromium picolinate 3-Hydroxypyridine 3,5-Dihydroxybenzoic acid Zinc picolinate 2-Picolinic acid phosphoric acid 3-Hydroxypicolinic acid CHLOROPHOSPHONAZO III Citric acid

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